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Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.

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Title: Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
Authors: Baidya M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Chaturvedi M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Dwivedi-Agnihotri H; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Ranjan A; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Devost D; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada., Namkung Y; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada., Stepniewski TM; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Warsaw, Poland., Pandey S; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Baruah M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Panigrahi B; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Sarma P; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Yadav MK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Maharana J; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Banerjee R; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Kawakami K; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan., Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan., Selent J; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain., Laporte SA; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada., Hébert TE; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada., Shukla AK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India. arshukla@iitk.ac.in.
Source: Nature communications [Nat Commun] 2022 Aug 08; Vol. 13 (1), pp. 4634. Date of Electronic Publication: 2022 Aug 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Baidya+M%22">Baidya M</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Chaturvedi+M%22">Chaturvedi M</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Dwivedi-Agnihotri+H%22">Dwivedi-Agnihotri H</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Ranjan+A%22">Ranjan A</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Devost+D%22">Devost D</searchLink>; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.<br /><searchLink fieldCode="AU" term="%22Namkung+Y%22">Namkung Y</searchLink>; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada.<br /><searchLink fieldCode="AU" term="%22Stepniewski+TM%22">Stepniewski TM</searchLink>; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Pandey+S%22">Pandey S</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Baruah+M%22">Baruah M</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Panigrahi+B%22">Panigrahi B</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Sarma+P%22">Sarma P</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Yadav+MK%22">Yadav MK</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Maharana+J%22">Maharana J</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Banerjee+R%22">Banerjee R</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.<br /><searchLink fieldCode="AU" term="%22Kawakami+K%22">Kawakami K</searchLink>; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+A%22">Inoue A</searchLink>; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.<br /><searchLink fieldCode="AU" term="%22Selent+J%22">Selent J</searchLink>; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Laporte+SA%22">Laporte SA</searchLink>; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada.<br /><searchLink fieldCode="AU" term="%22Hébert+TE%22">Hébert TE</searchLink>; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.<br /><searchLink fieldCode="AU" term="%22Shukla+AK%22">Shukla AK</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India. arshukla@iitk.ac.in.
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