Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
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| Title: | Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody. |
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| Authors: | Baidya M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Chaturvedi M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Dwivedi-Agnihotri H; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Ranjan A; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Devost D; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada., Namkung Y; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada., Stepniewski TM; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Warsaw, Poland., Pandey S; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Baruah M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Panigrahi B; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Sarma P; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Yadav MK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Maharana J; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Banerjee R; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India., Kawakami K; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan., Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan., Selent J; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain., Laporte SA; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada., Hébert TE; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada., Shukla AK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India. arshukla@iitk.ac.in. |
| Source: | Nature communications [Nat Commun] 2022 Aug 08; Vol. 13 (1), pp. 4634. Date of Electronic Publication: 2022 Aug 08. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-32386-x |