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Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies.

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Title: Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies.
Authors: Ali M; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; School for Mental Health and Neuroscience (MHeNs), Department of Psychiatry and Neuropsychology, Maastricht University, 6200, Maastricht, the Netherlands., Huarte OU; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg., Heurtaux T; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, L‑4362, Esch-Sur-Alzette, Luxembourg., Garcia P; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg., Rodriguez BP; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.; University of the Basque Country, Cell Biology and Histology Department, 48940, Leioa, Vizcaya, Basque Country, Spain., Grzyb K; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg., Halder R; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg., Skupin A; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Department of Physics and Materials Science, University of Luxembourg, 162a av. de la Faïencerie, 1511, Luxembourg, Luxembourg.; Department of Neuroscience, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, 92093, USA., Buttini M; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg., Glaab E; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg. enrico.glaab@uni.lu.
Source: Molecular neurobiology [Mol Neurobiol] 2024 Feb; Vol. 61 (2), pp. 541-566. Date of Electronic Publication: 2022 Aug 18.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies.
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  Data: <searchLink fieldCode="AU" term="%22Ali+M%22">Ali M</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; School for Mental Health and Neuroscience (MHeNs), Department of Psychiatry and Neuropsychology, Maastricht University, 6200, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Huarte+OU%22">Huarte OU</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Heurtaux+T%22">Heurtaux T</searchLink>; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.; Department of Life Sciences and Medicine (DLSM), University of Luxembourg, L‑4362, Esch-Sur-Alzette, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Garcia+P%22">Garcia P</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Rodriguez+BP%22">Rodriguez BP</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.; University of the Basque Country, Cell Biology and Histology Department, 48940, Leioa, Vizcaya, Basque Country, Spain.<br /><searchLink fieldCode="AU" term="%22Grzyb+K%22">Grzyb K</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Halder+R%22">Halder R</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Skupin+A%22">Skupin A</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Department of Physics and Materials Science, University of Luxembourg, 162a av. de la Faïencerie, 1511, Luxembourg, Luxembourg.; Department of Neuroscience, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Buttini+M%22">Buttini M</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Glaab+E%22">Glaab E</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7 avenue des Hauts Fourneaux, L-4362, Esch-sur-Alzette, Luxembourg. enrico.glaab@uni.lu.
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  Data: <searchLink fieldCode="JN" term="%228900963%22">Molecular neurobiology</searchLink> [Mol Neurobiol] 2024 Feb; Vol. 61 (2), pp. 541-566. <i>Date of Electronic Publication: </i>2022 Aug 18.
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              Text: 2024 Feb
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