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The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance.

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Title: The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance.
Authors: Klein AB; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nicolaisen TS; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; The August Krogh Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Johann K; German Center for Diabetes Research (DZD), DIfE, Potsdam-Rehbrücke, Nuthetal, Germany; Muscle Physiology and Metabolism Group, German Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, Nuthetal, Germany., Fritzen AM; The August Krogh Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Mathiesen CV; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gil C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pilmark NS; Centre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark., Karstoft K; Centre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark; Department of Clinical Pharmacology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark., Blond MB; Clinical Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Gentofte, Denmark., Quist JS; Clinical Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Gentofte, Denmark., Seeley RJ; Department of Surgery, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Færch K; Clinical Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Gentofte, Denmark; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Lund J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kleinert M; The August Krogh Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark; German Center for Diabetes Research (DZD), DIfE, Potsdam-Rehbrücke, Nuthetal, Germany; Muscle Physiology and Metabolism Group, German Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, Nuthetal, Germany. Electronic address: maximilian.kleinert@dife.de., Clemmensen C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: chc@sund.ku.dk.
Source: Cell reports [Cell Rep] 2022 Aug 23; Vol. 40 (8), pp. 111258.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance.
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  Data: <searchLink fieldCode="AU" term="%22Klein+AB%22">Klein AB</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Nicolaisen+TS%22">Nicolaisen TS</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; The August Krogh Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Johann+K%22">Johann K</searchLink>; German Center for Diabetes Research (DZD), DIfE, Potsdam-Rehbrücke, Nuthetal, Germany; Muscle Physiology and Metabolism Group, German Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Fritzen+AM%22">Fritzen AM</searchLink>; The August Krogh Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Mathiesen+CV%22">Mathiesen CV</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gil+C%22">Gil C</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pilmark+NS%22">Pilmark NS</searchLink>; Centre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Karstoft+K%22">Karstoft K</searchLink>; Centre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark; Department of Clinical Pharmacology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Blond+MB%22">Blond MB</searchLink>; Clinical Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Gentofte, Denmark.<br /><searchLink fieldCode="AU" term="%22Quist+JS%22">Quist JS</searchLink>; Clinical Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Gentofte, Denmark.<br /><searchLink fieldCode="AU" term="%22Seeley+RJ%22">Seeley RJ</searchLink>; Department of Surgery, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Færch+K%22">Færch K</searchLink>; Clinical Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Gentofte, Denmark; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lund+J%22">Lund J</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kleinert+M%22">Kleinert M</searchLink>; The August Krogh Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark; German Center for Diabetes Research (DZD), DIfE, Potsdam-Rehbrücke, Nuthetal, Germany; Muscle Physiology and Metabolism Group, German Institute of Human Nutrition (DIfE), Potsdam-Rehbrücke, Nuthetal, Germany. Electronic address: maximilian.kleinert@dife.de.<br /><searchLink fieldCode="AU" term="%22Clemmensen+C%22">Clemmensen C</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: chc@sund.ku.dk.
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