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Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-Gangliosidosis.

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Title: Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-Gangliosidosis.
Authors: Weesner JA; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Department of Anatomy and Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Annunziata I; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Compliance Office, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Yang T; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA., Acosta W; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA., Gomero E; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Hu H; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., van de Vlekkert D; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Ayala J; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA., Qiu X; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Fremuth LE; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Radin DN; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA., Cramer CL; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA., d'Azzo A; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Department of Anatomy and Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Source: Cells [Cells] 2022 Aug 19; Vol. 11 (16). Date of Electronic Publication: 2022 Aug 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-Gangliosidosis.
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  Data: <searchLink fieldCode="AU" term="%22Weesner+JA%22">Weesner JA</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Department of Anatomy and Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.<br /><searchLink fieldCode="AU" term="%22Annunziata+I%22">Annunziata I</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Compliance Office, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Yang+T%22">Yang T</searchLink>; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA.<br /><searchLink fieldCode="AU" term="%22Acosta+W%22">Acosta W</searchLink>; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA.<br /><searchLink fieldCode="AU" term="%22Gomero+E%22">Gomero E</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Hu+H%22">Hu H</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22van+de+Vlekkert+D%22">van de Vlekkert D</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Ayala+J%22">Ayala J</searchLink>; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA.<br /><searchLink fieldCode="AU" term="%22Qiu+X%22">Qiu X</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Fremuth+LE%22">Fremuth LE</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.<br /><searchLink fieldCode="AU" term="%22Radin+DN%22">Radin DN</searchLink>; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA.<br /><searchLink fieldCode="AU" term="%22Cramer+CL%22">Cramer CL</searchLink>; BioStrategies, LC, P.O. Box 2428, State University, Jonesboro, AR 72467, USA.<br /><searchLink fieldCode="AU" term="%22d'Azzo+A%22">d'Azzo A</searchLink>; Department of Genetics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Department of Anatomy and Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
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  Data: <searchLink fieldCode="JN" term="%22101600052%22">Cells</searchLink> [Cells] 2022 Aug 19; Vol. 11 (16). <i>Date of Electronic Publication: </i>2022 Aug 19.
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