Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia.
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| Title: | Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia. |
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| Authors: | Bergeron BP; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Diedrich JD; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Zhang Y; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Barnett KR; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Dong Q; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Ferguson DC; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Autry RJ; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA., Yang W; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Hansen BS; Department of Cell and Molecular Biology and Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, USA., Smith C; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Crews KR; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Fan Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Pui CH; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Pruett-Miller SM; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Cell and Molecular Biology and Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, USA., Relling MV; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Yang JJ; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA., Li C; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Evans WE; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Savic D; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA. daniel.savic@stjude.org.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. daniel.savic@stjude.org.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. daniel.savic@stjude.org.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA. daniel.savic@stjude.org. |
| Source: | Leukemia [Leukemia] 2022 Oct; Vol. 36 (10), pp. 2374-2383. Date of Electronic Publication: 2022 Aug 26. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36028659 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bergeron+BP%22">Bergeron BP</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Diedrich+JD%22">Diedrich JD</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Barnett+KR%22">Barnett KR</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Dong+Q%22">Dong Q</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Ferguson+DC%22">Ferguson DC</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Autry+RJ%22">Autry RJ</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+BS%22">Hansen BS</searchLink>; Department of Cell and Molecular Biology and Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Smith+C%22">Smith C</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Crews+KR%22">Crews KR</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Fan+Y%22">Fan Y</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Pui+CH%22">Pui CH</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Pruett-Miller+SM%22">Pruett-Miller SM</searchLink>; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Cell and Molecular Biology and Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Relling+MV%22">Relling MV</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Yang+JJ%22">Yang JJ</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Evans+WE%22">Evans WE</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Savic+D%22">Savic D</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA. daniel.savic@stjude.org.; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. daniel.savic@stjude.org.; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. daniel.savic@stjude.org.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA. daniel.savic@stjude.org. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2022 Oct; Vol. 36 (10), pp. 2374-2383. <i>Date of Electronic Publication: </i>2022 Aug 26. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41375-022-01685-z Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2374 Titles: – TitleFull: Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bergeron BP – PersonEntity: Name: NameFull: Diedrich JD – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Barnett KR – PersonEntity: Name: NameFull: Dong Q – PersonEntity: Name: NameFull: Ferguson DC – PersonEntity: Name: NameFull: Autry RJ – PersonEntity: Name: NameFull: Yang W – PersonEntity: Name: NameFull: Hansen BS – PersonEntity: Name: NameFull: Smith C – PersonEntity: Name: NameFull: Crews KR – PersonEntity: Name: NameFull: Fan Y – PersonEntity: Name: NameFull: Pui CH – PersonEntity: Name: NameFull: Pruett-Miller SM – PersonEntity: Name: NameFull: Relling MV – PersonEntity: Name: NameFull: Yang JJ – PersonEntity: Name: NameFull: Li C – PersonEntity: Name: NameFull: Evans WE – PersonEntity: Name: NameFull: Savic D IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2022 Oct Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1476-5551 Numbering: – Type: volume Value: 36 – Type: issue Value: 10 Titles: – TitleFull: Leukemia Type: main |
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