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A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.

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Title: A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Authors: Moore KP; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Schwaid AG; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Tudor M; Computational and Structural Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Park S; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Beshore DC; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Converso A; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Shipe WD; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Anand R; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Lan P; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Moningka R; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Rothman DM; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Sun W; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Chi A; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Cornella-Taracido I; Chemical Biology, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Adam GC; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Bahnck-Teets C; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Carroll SS; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Fay JF; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Goh SL; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Lusen J; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Quan S; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Rodriguez S; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Xu M; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Andrews CL; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Song C; Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Filzen T; Screening and Protein Sciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Li J; Screening and Protein Sciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Hollenstein K; Computational and Structural Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Klein DJ; Computational and Structural Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Lammens A; Proteros Biostructures GmbH, Bunsenstr, Martinsried 82152, Germany., Lim UM; Genome and Biomarker Sciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Fang Z; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States., McHale C; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Li Y; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Lu M; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Diamond TL; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Howell BJ; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Zuck P; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Balibar CJ; Infectious Disease and Vaccines, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Source: ACS chemical biology [ACS Chem Biol] 2022 Sep 16; Vol. 17 (9), pp. 2595-2604. Date of Electronic Publication: 2022 Aug 31.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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