Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.
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| Title: | Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. |
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| Authors: | Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. zhe.wang@mssm.edu., Emmerich A; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Pillon NJ; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Moore T; Division of Cardiology, Department of Medicine, University of California, Los Angeles, CA, USA., Hemerich D; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Mazzaferro E; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden., Broos S; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium.; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Physical Activity, Sports & Health Research Group, KU Leuven, Leuven, Belgium., Ahluwalia TS; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Bioinformatics Center, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Bartz TM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Chong M; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; GlaxoSmithKline, Cambridge, MA, USA., Berry D; Division of Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK., Dorajoo R; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore., Dueker ND; John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.; Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, USA., Kasbohm E; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Institute of Mathematics and Computer Science, University of Greifswald, Greifswald, Germany., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Hall LM; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Haller T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Hartwig FP; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.; MRC Integrative Epidemiology Unit, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK., Hillis DA; Genetics, Genomics, and Bioinformatics Graduate Program, University of California, Riverside, CA, USA., Huikari V; Institute of Health Sciences, University of Oulu, Oulu, Finland., Heard-Costa N; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Holzapfel C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany.; Institute for Nutritional Medicine, School of Medicine, Technical University of Munich, Munich, Germany., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Jørgensen AM; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kaakinen MA; Section of Statistical Multi-omics, Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kerr KF; Department of Biostatistics, University of Washington, Seattle, WA, USA., Kim B; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea., Koolhaas CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Kutalik Z; University Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland., Lagou V; Wellcome Sanger Institute, Cambridge, UK., Lind PA; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Biomedical Science, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia., Lorentzon M; Geriatric Medicine, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital Mölndal, Gothenburg, Sweden.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Mangino M; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK., Metzendorf C; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden., Monroe KR; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Pacolet A; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium., Pérusse L; Department of Kinesiology, Université Laval, Quebec, Quebec, Canada.; Centre Nutrition Santé et Société (NUTRISS), Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, Quebec, Canada., Pool R; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Richmond RC; MRC Integrative Epidemiology Unit and Avon Longitudinal Study of Parents and Children, University of Bristol Medical School, Population Health Sciences and Avon Longitudinal Study of Parents and Children, University of Bristol, Bristol, UK., Rivera NV; Respiratory Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Rheumatology Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Center of Molecular Medicine (CMM), Karolinska Institutet, Stockholm, Sweden., Robiou-du-Pont S; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Schraut KE; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Schulz CA; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Nutrition and Food Sciences, Nutritional Epidemiology, University of Bonn, Bonn, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Vanmunster M; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium., van Rooij FJA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Zhang X; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; School of Public Health, Department of Biostatistics, Shandong University, Jinan, China., Zhao JH; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Balkhiyarova Z; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Department of Clinical and Experimental Medicine, University of Surrey, Guilford, UK.; People-Centred Artificial Intelligence Institute, University of Surrey, Guilford, UK., Balslev-Harder MN; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Baumeister SE; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; University of Münster, Münster, Germany., Beilby J; Diagnostic Genomics, PathWest Laboratory Medicine WA, Perth, Western Australia, Australia., Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, TX, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Brage S; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Bruinenberg M; Lifelines Cohort Study, Groningen, the Netherlands., Ekelund U; Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.; Department of Chronic Diseases, Norwegian Institute of Public Health, Oslo, Norway., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Cole JW; Vascular Neurology, Department of Neurology, University of Maryland School of Medicine and the Baltimore VAMC, Baltimore, MD, USA., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Cupples LA; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fernandez-Rhodes L; Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, PA, USA., Fohner AE; Department of Epidemiology, Institute of Public Health Genetics, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Franco OH; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland., Galesloot TE; Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands., Gordon SD; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hartman CA; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Heiss G; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Hui J; Diagnostic Genomics, PathWest Laboratory Medicine WA, Perth, Western Australia, Australia.; School of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.; Busselton Population Medical Research Institute, Busselton, Western Australia, Australia., Illig T; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Department of Human Genetics, Hannover Medical School, Hannover, Germany., Jago R; Centre for Exercise Nutrition & Health Sciences, School for Policy Studies, University of Bristol, Bristol, UK., James A; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Western Australia, Perth, Australia., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Humanity Inc, Boston, MA, USA., Jung T; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea., Kähönen M; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Koh WP; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore, Singapore., Kolcic I; Department of Public Health, University of Split School of Medicine, Split, Croatia., Kraft PP; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institutes of Health, Baltimore, MD, USA., Li A; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Vidal PM; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Medland SE; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Psychology and Faculty of Medicine, University of Queensland, St Lucia, Queensland, Australia., Milaneschi Y; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands., Moscati A; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Musk B; Busselton Population Medical Research Institute, Busselton, Western Australia, Australia., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Peters A; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Power C; Division of Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK., Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Reedik M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rudan I; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Ryan K; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Sarzynski MA; Department of Exercise Science, University of South Carolina, Columbia, SC, USA., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Sidney S; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Siggeirsdottir K; Icelandic Heart Association, Kópavogur, Iceland., Smith AV; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Icelandic Heart Association, Kópavogur, Iceland., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Sonestedt E; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Strøm M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Faculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Teo KK; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Thorand B; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Tönjes A; Department of Medicine, University of Leipzig, Leipzig, Germany., Tremblay A; Department of Kinesiology, Université Laval, Quebec, Quebec, Canada.; Centre Nutrition Santé et Société (NUTRISS), Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, Quebec, Canada., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Vangipurapu J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., van Schoor N; Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, the Netherlands., Völker U; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Willemsen G; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Williams K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Wong Q; Department of Biostatistics, University of Washington, Seattle, WA, USA., Xu H; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Yuan JM; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Zillikens MC; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Zonderman AB; Laboratory of Epidemiology and Population Science, National Instiute on Aging, National Institutes of Health, Bethesda, MD, USA., Ameur A; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Bandinelli S; Geriatric Unit, Azienda USL Toscana Centro, Florence, Italy., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Smith GD; MRC Integrative Epidemiology Unit, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK.; Population Health Science, Bristol Medical School, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK., de Geus EJC; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Deldicque L; Faculty of Movement and Rehabilitation Sciences, Institute of Neuroscience, UC Louvain, Louvain-la-Neuve, Belgium., Dörr M; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Evans MK; Laboratory of Epidemiology and Population Science, National Instiute on Aging, National Institutes of Health, Bethesda, MD, USA., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Fox C; Genetics and Pharmacogenomics (GpGx), Merck Research Labs, Boston, MA, USA., Garland T Jr; Department of Evolution, Ecology, and Organismal Biology, University of California, Riverside, Riverside, CA, USA., Gudnason V; Icelandic Heart Association, Kópavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Horta BL; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Hyppönen E; Australian Centre for Precision Health, Unit of Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK., Jarvelin MR; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics and HPA-MRC Center, School of Public Health, Imperial College London, London, UK., Johnson WC; Department of Biostatistics, University of Washington, Seattle, WA, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kiemeney LA; Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Marchand LL; Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Martin NG; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Melbye M; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; K.G.Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Meyre D; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Orho-Melander M; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Pare G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Park T; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.; Department of Statistics, Seoul National University, Seoul, South Korea., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Penninx BWJH; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Polasek O; University of Split School of Medicine, Split, Croatia., Prokopenko I; Department of Clinical and Experimental Medicine, University of Surrey, Guilford, UK.; People-Centred Artificial Intelligence Institute, University of Surrey, Guilford, UK.; UMR 8199 - EGID, Institut Pasteur de Lille, CNRS, University of Lille, Lille, France., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Sim X; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Spector TD; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol Medical School, University of Bristol, Bristol, UK., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University, Washington, DC, USA., van der Velde N; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.; Section of Geriatrics, Department of Internal Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health, Aging and Later Life, Amsterdam, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Vollenweider P; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany., Voortman T; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Waeber G; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Wichmann HE; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Hevener AL; Division of Endocrinology, Department of Medicine, University of California, Los Angeles, CA, USA., Krook A; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Zierath JR; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Thomis MAI; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Physical Activity, Sports & Health Research Group, KU Leuven, Leuven, Belgium., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hoed MD; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden. marcel.den_hoed@igp.uu.se. |
| Corporate Authors: | Lifelines Cohort Study |
| Source: | Nature genetics [Nat Genet] 2022 Sep; Vol. 54 (9), pp. 1332-1344. Date of Electronic Publication: 2022 Sep 07. |
| Publication Type: | Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36071172 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. zhe.wang@mssm.edu.<br /><searchLink fieldCode="AU" term="%22Emmerich+A%22">Emmerich A</searchLink>; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Pillon+NJ%22">Pillon NJ</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Moore+T%22">Moore T</searchLink>; Division of Cardiology, Department of Medicine, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hemerich+D%22">Hemerich D</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cornelis+MC%22">Cornelis MC</searchLink>; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Mazzaferro+E%22">Mazzaferro E</searchLink>; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Broos+S%22">Broos S</searchLink>; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium.; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Physical Activity, Sports & Health Research Group, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Ahluwalia+TS%22">Ahluwalia TS</searchLink>; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Bioinformatics Center, Department of Biology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bartz+TM%22">Bartz TM</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bentley+AR%22">Bentley AR</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bielak+LF%22">Bielak LF</searchLink>; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Chong+M%22">Chong M</searchLink>; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chu+AY%22">Chu AY</searchLink>; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; GlaxoSmithKline, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Berry+D%22">Berry D</searchLink>; Division of Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Dorajoo+R%22">Dorajoo R</searchLink>; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Dueker+ND%22">Dueker ND</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.; Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kasbohm+E%22">Kasbohm E</searchLink>; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Institute of Mathematics and Computer Science, University of Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Feenstra+B%22">Feenstra B</searchLink>; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Feitosa+MF%22">Feitosa MF</searchLink>; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gieger+C%22">Gieger C</searchLink>; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Graff+M%22">Graff M</searchLink>; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Hall+LM%22">Hall LM</searchLink>; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Haller+T%22">Haller T</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Hartwig+FP%22">Hartwig FP</searchLink>; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.; MRC Integrative Epidemiology Unit, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Hillis+DA%22">Hillis DA</searchLink>; Genetics, Genomics, and Bioinformatics Graduate Program, University of California, Riverside, CA, USA.<br /><searchLink fieldCode="AU" term="%22Huikari+V%22">Huikari V</searchLink>; Institute of Health Sciences, University of Oulu, Oulu, Finland.<br /><searchLink fieldCode="AU" term="%22Heard-Costa+N%22">Heard-Costa N</searchLink>; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Holzapfel+C%22">Holzapfel C</searchLink>; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany.; Institute for Nutritional Medicine, School of Medicine, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Jackson+AU%22">Jackson AU</searchLink>; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Johansson+Å%22">Johansson Å</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Jørgensen+AM%22">Jørgensen AM</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kaakinen+MA%22">Kaakinen MA</searchLink>; Section of Statistical Multi-omics, Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Karlsson+R%22">Karlsson R</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Kerr+KF%22">Kerr KF</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+B%22">Kim B</searchLink>; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Koolhaas+CM%22">Koolhaas CM</searchLink>; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kutalik+Z%22">Kutalik Z</searchLink>; University Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lagou+V%22">Lagou V</searchLink>; Wellcome Sanger Institute, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Lind+PA%22">Lind PA</searchLink>; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Biomedical Science, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Lorentzon+M%22">Lorentzon M</searchLink>; Geriatric Medicine, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital Mölndal, Gothenburg, Sweden.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Lyytikäinen+LP%22">Lyytikäinen LP</searchLink>; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Mangino+M%22">Mangino M</searchLink>; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Metzendorf+C%22">Metzendorf C</searchLink>; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Monroe+KR%22">Monroe KR</searchLink>; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pacolet+A%22">Pacolet A</searchLink>; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Pérusse+L%22">Pérusse L</searchLink>; Department of Kinesiology, Université Laval, Quebec, Quebec, Canada.; Centre Nutrition Santé et Société (NUTRISS), Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Pool+R%22">Pool R</searchLink>; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Richmond+RC%22">Richmond RC</searchLink>; MRC Integrative Epidemiology Unit and Avon Longitudinal Study of Parents and Children, University of Bristol Medical School, Population Health Sciences and Avon Longitudinal Study of Parents and Children, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Rivera+NV%22">Rivera NV</searchLink>; Respiratory Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Rheumatology Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Center of Molecular Medicine (CMM), Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Robiou-du-Pont+S%22">Robiou-du-Pont S</searchLink>; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Schraut+KE%22">Schraut KE</searchLink>; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Schulz+CA%22">Schulz CA</searchLink>; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Nutrition and Food Sciences, Nutritional Epidemiology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Stringham+HM%22">Stringham HM</searchLink>; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Teumer+A%22">Teumer A</searchLink>; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Turman+C%22">Turman C</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22van+der+Most+PJ%22">van der Most PJ</searchLink>; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vanmunster+M%22">Vanmunster M</searchLink>; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22van+Rooij+FJA%22">van Rooij FJA</searchLink>; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Vliet-Ostaptchouk+JV%22">van Vliet-Ostaptchouk JV</searchLink>; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; School of Public Health, Department of Biostatistics, Shandong University, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Zhao+JH%22">Zhao JH</searchLink>; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Balkhiyarova+Z%22">Balkhiyarova Z</searchLink>; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Department of Clinical and Experimental Medicine, University of Surrey, Guilford, UK.; People-Centred Artificial Intelligence Institute, University of Surrey, Guilford, UK.<br /><searchLink fieldCode="AU" term="%22Balslev-Harder+MN%22">Balslev-Harder MN</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Baumeister+SE%22">Baumeister SE</searchLink>; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Beilby+J%22">Beilby J</searchLink>; Diagnostic Genomics, PathWest Laboratory Medicine WA, Perth, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Blangero+J%22">Blangero J</searchLink>; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, TX, USA.<br /><searchLink fieldCode="AU" term="%22Boomsma+DI%22">Boomsma DI</searchLink>; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Brage+S%22">Brage S</searchLink>; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Braund+PS%22">Braund PS</searchLink>; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Brody+JA%22">Brody JA</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bruinenberg+M%22">Bruinenberg M</searchLink>; Lifelines Cohort Study, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ekelund+U%22">Ekelund U</searchLink>; Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.; Department of Chronic Diseases, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Liu+CT%22">Liu CT</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cole+JW%22">Cole JW</searchLink>; Vascular Neurology, Department of Neurology, University of Maryland School of Medicine and the Baltimore VAMC, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Collins+FS%22">Collins FS</searchLink>; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cupples+LA%22">Cupples LA</searchLink>; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Esko+T%22">Esko T</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Enroth+S%22">Enroth S</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Faul+JD%22">Faul JD</searchLink>; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Fernandez-Rhodes+L%22">Fernandez-Rhodes L</searchLink>; Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fohner+AE%22">Fohner AE</searchLink>; Department of Epidemiology, Institute of Public Health Genetics, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Franco+OH%22">Franco OH</searchLink>; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Galesloot+TE%22">Galesloot TE</searchLink>; Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Gordon+SD%22">Gordon SD</searchLink>; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Grarup+N%22">Grarup N</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hartman+CA%22">Hartman CA</searchLink>; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Heiss+G%22">Heiss G</searchLink>; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Hui+J%22">Hui J</searchLink>; Diagnostic Genomics, PathWest Laboratory Medicine WA, Perth, Western Australia, Australia.; School of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.; Busselton Population Medical Research Institute, Busselton, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Illig+T%22">Illig T</searchLink>; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Department of Human Genetics, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Jago+R%22">Jago R</searchLink>; Centre for Exercise Nutrition & Health Sciences, School for Policy Studies, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22James+A%22">James A</searchLink>; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Western Australia, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Joshi+PK%22">Joshi PK</searchLink>; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Humanity Inc, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jung+T%22">Jung T</searchLink>; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Kähönen+M%22">Kähönen M</searchLink>; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Kilpeläinen+TO%22">Kilpeläinen TO</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Koh+WP%22">Koh WP</searchLink>; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kolcic+I%22">Kolcic I</searchLink>; Department of Public Health, University of Split School of Medicine, Split, Croatia.<br /><searchLink fieldCode="AU" term="%22Kraft+PP%22">Kraft PP</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kuusisto+J%22">Kuusisto J</searchLink>; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Launer+LJ%22">Launer LJ</searchLink>; Laboratory of Epidemiology and Population Sciences, National Institutes of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Li+A%22">Li A</searchLink>; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Linneberg+A%22">Linneberg A</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Luan+J%22">Luan J</searchLink>; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Vidal+PM%22">Vidal PM</searchLink>; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Medland+SE%22">Medland SE</searchLink>; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Psychology and Faculty of Medicine, University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Milaneschi+Y%22">Milaneschi Y</searchLink>; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Moscati+A%22">Moscati A</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Musk+B%22">Musk B</searchLink>; Busselton Population Medical Research Institute, Busselton, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Nelson+CP%22">Nelson CP</searchLink>; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Nolte+IM%22">Nolte IM</searchLink>; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pedersen+NL%22">Pedersen NL</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Peters+A%22">Peters A</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Peyser+PA%22">Peyser PA</searchLink>; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Power+C%22">Power C</searchLink>; Division of Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Raitakari+OT%22">Raitakari OT</searchLink>; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Reedik+M%22">Reedik M</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Reiner+AP%22">Reiner AP</searchLink>; Department of Epidemiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ridker+PM%22">Ridker PM</searchLink>; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rudan+I%22">Rudan I</searchLink>; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Ryan+K%22">Ryan K</searchLink>; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sarzynski+MA%22">Sarzynski MA</searchLink>; Department of Exercise Science, University of South Carolina, Columbia, SC, USA.<br /><searchLink fieldCode="AU" term="%22Scott+LJ%22">Scott LJ</searchLink>; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Scott+RA%22">Scott RA</searchLink>; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Sidney+S%22">Sidney S</searchLink>; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.<br /><searchLink fieldCode="AU" term="%22Siggeirsdottir+K%22">Siggeirsdottir K</searchLink>; Icelandic Heart Association, Kópavogur, Iceland.<br /><searchLink fieldCode="AU" term="%22Smith+AV%22">Smith AV</searchLink>; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Icelandic Heart Association, Kópavogur, Iceland.<br /><searchLink fieldCode="AU" term="%22Smith+JA%22">Smith JA</searchLink>; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Sonestedt+E%22">Sonestedt E</searchLink>; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Strøm+M%22">Strøm M</searchLink>; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Faculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands.<br /><searchLink fieldCode="AU" term="%22Tai+ES%22">Tai ES</searchLink>; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Teo+KK%22">Teo KK</searchLink>; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Thorand+B%22">Thorand B</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Tönjes+A%22">Tönjes A</searchLink>; Department of Medicine, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Tremblay+A%22">Tremblay A</searchLink>; Department of Kinesiology, Université Laval, Quebec, Quebec, Canada.; Centre Nutrition Santé et Société (NUTRISS), Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Uitterlinden+AG%22">Uitterlinden AG</searchLink>; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vangipurapu+J%22">Vangipurapu J</searchLink>; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22van+Schoor+N%22">van Schoor N</searchLink>; Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Völker+U%22">Völker U</searchLink>; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Willemsen+G%22">Willemsen G</searchLink>; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Williams+K%22">Williams K</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Wong+Q%22">Wong Q</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Young+KL%22">Young KL</searchLink>; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+JM%22">Yuan JM</searchLink>; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zillikens+MC%22">Zillikens MC</searchLink>; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zonderman+AB%22">Zonderman AB</searchLink>; Laboratory of Epidemiology and Population Science, National Instiute on Aging, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ameur+A%22">Ameur A</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Bandinelli+S%22">Bandinelli S</searchLink>; Geriatric Unit, Azienda USL Toscana Centro, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Bis+JC%22">Bis JC</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Boehnke+M%22">Boehnke M</searchLink>; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Bouchard+C%22">Bouchard C</searchLink>; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA.<br /><searchLink fieldCode="AU" term="%22Chasman+DI%22">Chasman DI</searchLink>; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+GD%22">Smith GD</searchLink>; MRC Integrative Epidemiology Unit, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK.; Population Health Science, Bristol Medical School, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22de+Geus+EJC%22">de Geus EJC</searchLink>; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Deldicque+L%22">Deldicque L</searchLink>; Faculty of Movement and Rehabilitation Sciences, Institute of Neuroscience, UC Louvain, Louvain-la-Neuve, Belgium.<br /><searchLink fieldCode="AU" term="%22Dörr+M%22">Dörr M</searchLink>; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Evans+MK%22">Evans MK</searchLink>; Laboratory of Epidemiology and Population Science, National Instiute on Aging, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ferrucci+L%22">Ferrucci L</searchLink>; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Fornage+M%22">Fornage M</searchLink>; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Fox+C%22">Fox C</searchLink>; Genetics and Pharmacogenomics (GpGx), Merck Research Labs, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Garland+T+Jr%22">Garland T Jr</searchLink>; Department of Evolution, Ecology, and Organismal Biology, University of California, Riverside, Riverside, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gudnason+V%22">Gudnason V</searchLink>; Icelandic Heart Association, Kópavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Gyllensten+U%22">Gyllensten U</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Hansen+T%22">Hansen T</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hayward+C%22">Hayward C</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Horta+BL%22">Horta BL</searchLink>; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.<br /><searchLink fieldCode="AU" term="%22Hyppönen+E%22">Hyppönen E</searchLink>; Australian Centre for Precision Health, Unit of Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Jarvelin+MR%22">Jarvelin MR</searchLink>; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics and HPA-MRC Center, School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Johnson+WC%22">Johnson WC</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kardia+SLR%22">Kardia SLR</searchLink>; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Kiemeney+LA%22">Kiemeney LA</searchLink>; Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Laakso+M%22">Laakso M</searchLink>; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Langenberg+C%22">Langenberg C</searchLink>; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Lehtimäki+T%22">Lehtimäki T</searchLink>; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Marchand+LL%22">Marchand LL</searchLink>; Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Magnusson+PKE%22">Magnusson PKE</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Martin+NG%22">Martin NG</searchLink>; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Melbye+M%22">Melbye M</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; K.G.Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Metspalu+A%22">Metspalu A</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Meyre+D%22">Meyre D</searchLink>; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22North+KE%22">North KE</searchLink>; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ohlsson+C%22">Ohlsson C</searchLink>; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Oldehinkel+AJ%22">Oldehinkel AJ</searchLink>; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Orho-Melander+M%22">Orho-Melander M</searchLink>; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Pare+G%22">Pare G</searchLink>; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Park+T%22">Park T</searchLink>; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.; Department of Statistics, Seoul National University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Pedersen+O%22">Pedersen O</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Penninx+BWJH%22">Penninx BWJH</searchLink>; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pers+TH%22">Pers TH</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Polasek+O%22">Polasek O</searchLink>; University of Split School of Medicine, Split, Croatia.<br /><searchLink fieldCode="AU" term="%22Prokopenko+I%22">Prokopenko I</searchLink>; Department of Clinical and Experimental Medicine, University of Surrey, Guilford, UK.; People-Centred Artificial Intelligence Institute, University of Surrey, Guilford, UK.; UMR 8199 - EGID, Institut Pasteur de Lille, CNRS, University of Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Rotimi+CN%22">Rotimi CN</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Samani+NJ%22">Samani NJ</searchLink>; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Sim+X%22">Sim X</searchLink>; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Snieder+H%22">Snieder H</searchLink>; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Sørensen+TIA%22">Sørensen TIA</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Spector+TD%22">Spector TD</searchLink>; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Timpson+NJ%22">Timpson NJ</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22van+Dam+RM%22">van Dam RM</searchLink>; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22van+der+Velde+N%22">van der Velde N</searchLink>; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.; Section of Geriatrics, Department of Internal Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health, Aging and Later Life, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Duijn+CM%22">van Duijn CM</searchLink>; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Vollenweider+P%22">Vollenweider P</searchLink>; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Völzke+H%22">Völzke H</searchLink>; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Voortman+T%22">Voortman T</searchLink>; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Waeber+G%22">Waeber G</searchLink>; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wareham+NJ%22">Wareham NJ</searchLink>; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Weir+DR%22">Weir DR</searchLink>; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Wichmann+HE%22">Wichmann HE</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wilson+JF%22">Wilson JF</searchLink>; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Hevener+AL%22">Hevener AL</searchLink>; Division of Endocrinology, Department of Medicine, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Krook+A%22">Krook A</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Zierath+JR%22">Zierath JR</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Thomis+MAI%22">Thomis MAI</searchLink>; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Physical Activity, Sports & Health Research Group, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Loos+RJF%22">Loos RJF</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hoed+MD%22">Hoed MD</searchLink>; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden. marcel.den&#95;hoed@igp.uu.se. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Lifelines+Cohort+Study%22">Lifelines Cohort Study</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2022 Sep; Vol. 54 (9), pp. 1332-1344. <i>Date of Electronic Publication: </i>2022 Sep 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Co%22">Nature Pub. Co </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9216904 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-1718 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210614036%22">10614036 </searchLink><i>NLM ISO Abbreviation: </i>Nat Genet <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41588-022-01165-1 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1332 Titles: – TitleFull: Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. 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