A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.

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Title: A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.
Authors: Chaturvedi S; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037., Vasen G; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Pablo M; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Chen X; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Calia G; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Buie L; VxBiosciences Inc., Berkeley, CA 94707., Rodick R; VxBiosciences Inc., Berkeley, CA 94707., Smith D; Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, CA 92121., Rogers T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.; Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, CA 92121., Weinberger LS; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158.; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Sep 27; Vol. 119 (39), pp. e2204624119. Date of Electronic Publication: 2022 Sep 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.
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  Data: <searchLink fieldCode="AU" term="%22Chaturvedi+S%22">Chaturvedi S</searchLink>; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.<br /><searchLink fieldCode="AU" term="%22Beutler+N%22">Beutler N</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Vasen+G%22">Vasen G</searchLink>; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.<br /><searchLink fieldCode="AU" term="%22Pablo+M%22">Pablo M</searchLink>; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.<br /><searchLink fieldCode="AU" term="%22Calia+G%22">Calia G</searchLink>; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.<br /><searchLink fieldCode="AU" term="%22Buie+L%22">Buie L</searchLink>; VxBiosciences Inc., Berkeley, CA 94707.<br /><searchLink fieldCode="AU" term="%22Rodick+R%22">Rodick R</searchLink>; VxBiosciences Inc., Berkeley, CA 94707.<br /><searchLink fieldCode="AU" term="%22Smith+D%22">Smith D</searchLink>; Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, CA 92121.<br /><searchLink fieldCode="AU" term="%22Rogers+T%22">Rogers T</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.; Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, CA 92121.<br /><searchLink fieldCode="AU" term="%22Weinberger+LS%22">Weinberger LS</searchLink>; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158.; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2022 Sep 27; Vol. 119 (39), pp. e2204624119. <i>Date of Electronic Publication: </i>2022 Sep 08.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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