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IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.

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Title: IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.
Authors: Clement M; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK., Forbester JL; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK., Marsden M; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK., Sabberwal P; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK., Sommerville MS; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK., Wellington D; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Dimonte S; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK., Clare S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Harcourt K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Yin Z; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Nobre L; Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK., Antrobus R; Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK., Jin B; Fourth Military Medical University, Xian, China., Chen M; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, 06536, USA., Makvandi-Nejad S; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK., Lindborg JA; Departments of Neurology and Neuroscience, Yale University School of Medicine, New Haven, CT, 06520, USA., Strittmatter SM; Departments of Neurology and Neuroscience, Yale University School of Medicine, New Haven, CT, 06520, USA., Weekes MP; Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK., Stanton RJ; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK., Dong T; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Humphreys IR; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK. HumphreysIR@cardiff.ac.uk.
Source: Nature communications [Nat Commun] 2022 Sep 08; Vol. 13 (1), pp. 5294. Date of Electronic Publication: 2022 Sep 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.
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  Data: <searchLink fieldCode="AU" term="%22Clement+M%22">Clement M</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Forbester+JL%22">Forbester JL</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.<br /><searchLink fieldCode="AU" term="%22Marsden+M%22">Marsden M</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Sabberwal+P%22">Sabberwal P</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Sommerville+MS%22">Sommerville MS</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Wellington+D%22">Wellington D</searchLink>; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dimonte+S%22">Dimonte S</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Clare+S%22">Clare S</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Harcourt+K%22">Harcourt K</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Yin+Z%22">Yin Z</searchLink>; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Nobre+L%22">Nobre L</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Antrobus+R%22">Antrobus R</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Jin+B%22">Jin B</searchLink>; Fourth Military Medical University, Xian, China.<br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, 06536, USA.<br /><searchLink fieldCode="AU" term="%22Makvandi-Nejad+S%22">Makvandi-Nejad S</searchLink>; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.<br /><searchLink fieldCode="AU" term="%22Lindborg+JA%22">Lindborg JA</searchLink>; Departments of Neurology and Neuroscience, Yale University School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Strittmatter+SM%22">Strittmatter SM</searchLink>; Departments of Neurology and Neuroscience, Yale University School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Weekes+MP%22">Weekes MP</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Stanton+RJ%22">Stanton RJ</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Dong+T%22">Dong T</searchLink>; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, OX3 9DS, UK.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Humphreys+IR%22">Humphreys IR</searchLink>; Division of Infection and Immunity/Systems Immunity University Research Institute, Cardiff University, Cardiff, CF14 4XN, UK. HumphreysIR@cardiff.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Sep 08; Vol. 13 (1), pp. 5294. <i>Date of Electronic Publication: </i>2022 Sep 08.
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