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Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML.

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Title: Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML.
Authors: Nguyen NHK; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL., Rafiee R; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL., Tagmount A; Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL., Sobh A; UF Health Cancer Center, Gainesville, FL., Loguinov A; Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL., de Jesus Sosa AK; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL., Elsayed AH; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL., Gbadamosi M; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL., Seligson N; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Jacksonville, FL., Cogle CR; Division of Hematology and Oncology, Department of Medicine, University of Florida, Gainesville, FL., Rubnitz J; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Ribeiro R; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Downing J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN., Cao X; University of Tennessee Health Science Center, Memphis, TN., Pounds SB; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN., Vulpe CD; UF Health Cancer Center, Gainesville, FL., Lamba JK; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL.
Source: Blood advances [Blood Adv] 2023 May 09; Vol. 7 (9), pp. 1769-1783.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+NHK%22">Nguyen NHK</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Rafiee+R%22">Rafiee R</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Tagmount+A%22">Tagmount A</searchLink>; Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Sobh+A%22">Sobh A</searchLink>; UF Health Cancer Center, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Loguinov+A%22">Loguinov A</searchLink>; Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22de+Jesus+Sosa+AK%22">de Jesus Sosa AK</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Elsayed+AH%22">Elsayed AH</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Gbadamosi+M%22">Gbadamosi M</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Seligson+N%22">Seligson N</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Jacksonville, FL.<br /><searchLink fieldCode="AU" term="%22Cogle+CR%22">Cogle CR</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Rubnitz+J%22">Rubnitz J</searchLink>; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Ribeiro+R%22">Ribeiro R</searchLink>; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Downing+J%22">Downing J</searchLink>; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Cao+X%22">Cao X</searchLink>; University of Tennessee Health Science Center, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Pounds+SB%22">Pounds SB</searchLink>; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Vulpe+CD%22">Vulpe CD</searchLink>; UF Health Cancer Center, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Lamba+JK%22">Lamba JK</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL.
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  Data: <searchLink fieldCode="JN" term="%22101698425%22">Blood advances</searchLink> [Blood Adv] 2023 May 09; Vol. 7 (9), pp. 1769-1783.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
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        Value: 10.1182/bloodadvances.2022007934
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              Text: 2023 May 09
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