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Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors.

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Title: Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors.
Authors: Granieri L; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Marocchi F; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Melixetian M; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Mohammadi N; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy; Experimental Hematology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy., Nicoli P; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Cuomo A; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Bonaldi T; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Confalonieri S; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Pisati F; Histopathology Unit, Cogentech S.C.a.R.L, Via Adamello, 20139 Milan, Italy., Giardina G; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy., Bertalot G; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy; U.O.M. Anatomia ed Istologia Patologica, Ospedale S. Chiara di Trento, Largo Medaglie d'Oro, 38122 Trento, Italy., Bossi D; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy; Institute of Oncology Research, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Lanfrancone L; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy. Electronic address: luisa.lanfrancone@ieo.it.
Source: Cell reports [Cell Rep] 2022 Sep 20; Vol. 40 (12), pp. 111396.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Granieri+L%22">Granieri L</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Marocchi+F%22">Marocchi F</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Melixetian+M%22">Melixetian M</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mohammadi+N%22">Mohammadi N</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy; Experimental Hematology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Nicoli+P%22">Nicoli P</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cuomo+A%22">Cuomo A</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bonaldi+T%22">Bonaldi T</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Confalonieri+S%22">Confalonieri S</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pisati+F%22">Pisati F</searchLink>; Histopathology Unit, Cogentech S.C.a.R.L, Via Adamello, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Giardina+G%22">Giardina G</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bertalot+G%22">Bertalot G</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy; U.O.M. Anatomia ed Istologia Patologica, Ospedale S. Chiara di Trento, Largo Medaglie d'Oro, 38122 Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Bossi+D%22">Bossi D</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy; Institute of Oncology Research, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lanfrancone+L%22">Lanfrancone L</searchLink>; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy. Electronic address: luisa.lanfrancone@ieo.it.
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