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Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.

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Title: Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.
Authors: Mishra N; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Aden K; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Blase JI; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Baran N; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Bordoni D; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Tran F; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Conrad C; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Avalos D; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland., Jaeckel C; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Scherer M; Department of Genetics, University of Saarland, Saarbrücken, Germany.; Present address: Department of Bioinformatics and Genomics, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, 08003, Barcelona, Spain., Sørensen SB; The Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Overgaard SH; The Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Schulte B; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Nikolaus S; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Rey G; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland., Gasparoni G; Department of Genetics, University of Saarland, Saarbrücken, Germany., Lyons PA; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge, CB 0AW, UK.; Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Schultze JL; Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE), and University of Bonn, Bonn, Germany., Walter J; Department of Genetics, University of Saarland, Saarbrücken, Germany., Andersen V; The Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Dermitzakis ET; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland., Schreiber S; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany. s.schreiber@mucosa.de.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany. s.schreiber@mucosa.de., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany. p.rosenstiel@mucosa.de.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany. p.rosenstiel@mucosa.de.
Corporate Authors: SYSCID Consortium
Source: Genome medicine [Genome Med] 2022 Sep 24; Vol. 14 (1), pp. 110. Date of Electronic Publication: 2022 Sep 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.
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  Data: <searchLink fieldCode="AU" term="%22Mishra+N%22">Mishra N</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Aden+K%22">Aden K</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Blase+JI%22">Blase JI</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Baran+N%22">Baran N</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Bordoni+D%22">Bordoni D</searchLink>; 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  Data: <searchLink fieldCode="JN" term="%22101475844%22">Genome medicine</searchLink> [Genome Med] 2022 Sep 24; Vol. 14 (1), pp. 110. <i>Date of Electronic Publication: </i>2022 Sep 24.
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