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Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability.

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Title: Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability.
Authors: Shukla PK; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Sinha D; IHU, Aix Marseille University, Marseille, France., Leng AM; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Bissell JE; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Thatipamula S; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Ganguly R; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Radmall KS; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Skalicky JJ; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, USA., Shrieve DC; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Chandrasekharan MB; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA. Electronic address: mahesh.chandrasekharan@hci.utah.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2022 Nov; Vol. 298 (11), pp. 102524. Date of Electronic Publication: 2022 Sep 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability.
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  Data: <searchLink fieldCode="AU" term="%22Shukla+PK%22">Shukla PK</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Sinha+D%22">Sinha D</searchLink>; IHU, Aix Marseille University, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Leng+AM%22">Leng AM</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Bissell+JE%22">Bissell JE</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Thatipamula+S%22">Thatipamula S</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Ganguly+R%22">Ganguly R</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Radmall+KS%22">Radmall KS</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Skalicky+JJ%22">Skalicky JJ</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Shrieve+DC%22">Shrieve DC</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Chandrasekharan+MB%22">Chandrasekharan MB</searchLink>; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA. Electronic address: mahesh.chandrasekharan@hci.utah.edu.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2022 Nov; Vol. 298 (11), pp. 102524. <i>Date of Electronic Publication: </i>2022 Sep 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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              Text: 2022 Nov
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