Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects. - Chatturong U; Martin H; Totoson P; Ingkaninan K; Temkitthawon P; Sermsenaphorn S; Somarin T; Konsue A; Gleeson MP; Demougeot C; Chootip K (Vascular pharmacology, 2022)