Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidity.

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Title:	Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidity.
Authors:	Lau MC; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Yi Y; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore., Goh D; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Cheung CCL; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Tan B; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lim JCT; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Joseph CR; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Wee F; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lee JN; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lim X; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lim CJ; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Lee JY; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore., Ng CCY; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore., Bashiri H; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Cheow PC; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Chan CY; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Koh YX; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Tan TT; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore., Kalimuddin S; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore., Tai WMD; National Cancer Centre Singapore, Division of Medical Oncology, Singapore, Singapore., Ng JL; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore., Low JG; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore., Lim TKH; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Liu J; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore., Yeong JPS; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Source:	Frontiers in immunology [Front Immunol] 2022 Sep 12; Vol. 13, pp. 978760. Date of Electronic Publication: 2022 Sep 12 (Print Publication: 2022).
Publication Type:	Case Reports; Research Support, Non-U.S. Gov't; Journal Article
Journal Info:	Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1664-3224
DOI:	10.3389/fimmu.2022.978760