View in EDS PDF Full Text

Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidity.

Saved in:
Bibliographic Details
Title: Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidity.
Authors: Lau MC; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Yi Y; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore., Goh D; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Cheung CCL; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Tan B; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lim JCT; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Joseph CR; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Wee F; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lee JN; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lim X; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Lim CJ; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Lee JY; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore., Ng CCY; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore., Bashiri H; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore., Cheow PC; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Chan CY; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Koh YX; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore., Tan TT; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore., Kalimuddin S; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore., Tai WMD; National Cancer Centre Singapore, Division of Medical Oncology, Singapore, Singapore., Ng JL; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore., Low JG; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore., Lim TKH; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Liu J; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore., Yeong JPS; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Source: Frontiers in immunology [Front Immunol] 2022 Sep 12; Vol. 13, pp. 978760. Date of Electronic Publication: 2022 Sep 12 (Print Publication: 2022).
Publication Type: Case Reports; Research Support, Non-U.S. Gov't; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36172383
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidity.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Lau+MC%22">Lau MC</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yi+Y%22">Yi Y</searchLink>; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Goh+D%22">Goh D</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheung+CCL%22">Cheung CCL</searchLink>; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+B%22">Tan B</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+JCT%22">Lim JCT</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Joseph+CR%22">Joseph CR</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wee+F%22">Wee F</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+JN%22">Lee JN</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+X%22">Lim X</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+CJ%22">Lim CJ</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Leow+WQ%22">Leow WQ</searchLink>; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ng+CCY%22">Ng CCY</searchLink>; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Bashiri+H%22">Bashiri H</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheow+PC%22">Cheow PC</searchLink>; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chan+CY%22">Chan CY</searchLink>; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Koh+YX%22">Koh YX</searchLink>; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+TT%22">Tan TT</searchLink>; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kalimuddin+S%22">Kalimuddin S</searchLink>; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tai+WMD%22">Tai WMD</searchLink>; National Cancer Centre Singapore, Division of Medical Oncology, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ng+JL%22">Ng JL</searchLink>; Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Low+JG%22">Low JG</searchLink>; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+TKH%22">Lim TKH</searchLink>; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yeong+JPS%22">Yeong JPS</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency of Science, Technology and Research (ASTAR), Singapore, Singapore.; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2022 Sep 12; Vol. 13, pp. 978760. <i>Date of Electronic Publication: </i>2022 Sep 12 (<i>Print Publication: </i>2022).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Case Reports; Research Support, Non-U.S. Gov't; Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36172383
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3389/fimmu.2022.978760
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 978760
    Titles:
      – TitleFull: Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidity.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Lau MC
      – PersonEntity:
          Name:
            NameFull: Yi Y
      – PersonEntity:
          Name:
            NameFull: Goh D
      – PersonEntity:
          Name:
            NameFull: Cheung CCL
      – PersonEntity:
          Name:
            NameFull: Tan B
      – PersonEntity:
          Name:
            NameFull: Lim JCT
      – PersonEntity:
          Name:
            NameFull: Joseph CR
      – PersonEntity:
          Name:
            NameFull: Wee F
      – PersonEntity:
          Name:
            NameFull: Lee JN
      – PersonEntity:
          Name:
            NameFull: Lim X
      – PersonEntity:
          Name:
            NameFull: Lim CJ
      – PersonEntity:
          Name:
            NameFull: Leow WQ
      – PersonEntity:
          Name:
            NameFull: Lee JY
      – PersonEntity:
          Name:
            NameFull: Ng CCY
      – PersonEntity:
          Name:
            NameFull: Bashiri H
      – PersonEntity:
          Name:
            NameFull: Cheow PC
      – PersonEntity:
          Name:
            NameFull: Chan CY
      – PersonEntity:
          Name:
            NameFull: Koh YX
      – PersonEntity:
          Name:
            NameFull: Tan TT
      – PersonEntity:
          Name:
            NameFull: Kalimuddin S
      – PersonEntity:
          Name:
            NameFull: Tai WMD
      – PersonEntity:
          Name:
            NameFull: Ng JL
      – PersonEntity:
          Name:
            NameFull: Low JG
      – PersonEntity:
          Name:
            NameFull: Lim TKH
      – PersonEntity:
          Name:
            NameFull: Liu J
      – PersonEntity:
          Name:
            NameFull: Yeong JPS
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 12
              M: 09
              Text: 2022 Sep 12
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1664-3224
          Numbering:
            – Type: volume
              Value: 13
          Titles:
            – TitleFull: Frontiers in immunology
              Type: main
ResultId 1