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ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma.

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Title: ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma.
Authors: Praveen K; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Patel GC; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Gurski L; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Ayer AH; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Persaud T; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Still MD; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Miloscio L; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Van Zyl T; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Di Gioia SA; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, 7030, Trondheim, Norway.; HUNT Research Center, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, 7600, Levanger, Norway.; Clinic of Medicine, St. Olavs Hospital Trondheim University Hospital, 7030, Trondheim, Norway., Krebs K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, 7030, Trondheim, Norway.; HUNT Research Center, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, 7600, Levanger, Norway.; Department of Endocrinology, Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, 7030, Trondheim, Norway., Chen E; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Chavali VRM; Department of Ophthalmology, Pearlman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Fury W; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Gudiseva HV; Department of Ophthalmology, Pearlman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hyde S; Alnylam Pharmaceuticals, Inc, Cambridge, MA, 02142, USA., Jorgenson E; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Lefebvre S; Alnylam Pharmaceuticals, Inc, Cambridge, MA, 02142, USA., Li D; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Li A; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Mclninch J; Alnylam Pharmaceuticals, Inc, Cambridge, MA, 02142, USA., Patel B; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Rabinowitz JS; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Salowe R; Department of Ophthalmology, Pearlman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Schurmann C; Bayer AG, Pharmaceuticals, Research and Development, 13342, Berlin, Germany., Seidelin AS; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Stahl E; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Sun D; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Teslovich TM; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Tybjærg-Hansen A; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Willer C; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Waldron S; Alnylam Pharmaceuticals, Inc, Cambridge, MA, 02142, USA., Walley S; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Yang H; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Zaveri S; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Hu Y; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, 7030, Trondheim, Norway.; HUNT Research Center, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, 7600, Levanger, Norway., Melander O; Lund University, Department of Clinical Sciences Malmö, Malmö, Sweden.; Skåne University Hospital, Department of Emergency and Internal Medicine, Malmö, Sweden., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Stender S; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., O'Brien JM; Department of Ophthalmology, Pearlman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Jones MB; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Abecasis GR; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Cantor MN; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Weyne J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Karalis K; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Economides A; Regeneron Genetics Center, Tarrytown, NY, 10591, USA.; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Della Gatta G; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Ferreira MA; Regeneron Genetics Center, Tarrytown, NY, 10591, USA., Yancopoulos GD; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA., Baras A; Regeneron Genetics Center, Tarrytown, NY, 10591, USA. aris.baras@regeneron.com., Romano C; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 10591, USA. carl.romano@regeneron.com., Coppola G; Regeneron Genetics Center, Tarrytown, NY, 10591, USA. giovanni.coppola@regeneron.com.
Corporate Authors: Regeneron Genetics Center, GHS-RGC DiscovEHR Collaboration, Estonian Biobank Research Team
Source: Communications biology [Commun Biol] 2022 Oct 03; Vol. 5 (1), pp. 1051. Date of Electronic Publication: 2022 Oct 03.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2399-3642
DOI:10.1038/s42003-022-03932-6