Coffee modulates insulin-hepatocyte nuclear factor-4α-Cyp7b1 pathway and reduces oxysterol-driven liver toxicity in a nonalcoholic fatty liver disease mouse model.

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Title:	Coffee modulates insulin-hepatocyte nuclear factor-4α-Cyp7b1 pathway and reduces oxysterol-driven liver toxicity in a nonalcoholic fatty liver disease mouse model.
Authors:	Kakiyama G; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia.; Central Virginia Veterans Affairs Healthcare System, Richmond, Virginia., Minowa K; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia.; Department of Pediatrics, Juntendo University Faculty of Medicine, Tokyo, Japan., Rodriguez-Agudo D; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia.; Central Virginia Veterans Affairs Healthcare System, Richmond, Virginia., Martin R; Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia., Takei H; Junshin Clinic Bile Acid Institute, Tokyo, Japan., Mitamura K; Faculty of Pharmacy, Kindai University, Osaka, Japan., Ikegawa S; Genmaikoso, Co. Ltd., Sapporo, Hokkaido, Japan., Suzuki M; Department of Pediatrics, Juntendo University Faculty of Medicine, Tokyo, Japan., Nittono H; Junshin Clinic Bile Acid Institute, Tokyo, Japan., Fuchs M; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia.; Central Virginia Veterans Affairs Healthcare System, Richmond, Virginia., Heuman DM; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia., Zhou H; Central Virginia Veterans Affairs Healthcare System, Richmond, Virginia.; Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia., Pandak WM; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia.; Central Virginia Veterans Affairs Healthcare System, Richmond, Virginia.; Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia.
Source:	American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2022 Nov 01; Vol. 323 (5), pp. G488-G500. Date of Electronic Publication: 2022 Oct 04.
Publication Type:	Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info:	Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1522-1547
DOI:	10.1152/ajpgi.00179.2022