View in EDS HTML Full Text PDF Full Text

Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.

Saved in:
Bibliographic Details
Title: Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.
Authors: Yang SJ; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA., Singh AK; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Drow T; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Tappen T; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA., Honaker Y; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Barahmand-Pour-Whitman F; Center for Systems Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA., Linsley PS; Center for Systems Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA., Cerosaletti K; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA., Mauk K; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA., Xiang Y; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Smith J; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Mortensen E; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA., Cook PJ; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Sommer K; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Khan I; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA., Liggitt D; Department of Comparative Medicine, University of Washington, Seattle, WA 98101, USA., Rawlings DJ; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA.; Department of Immunology, University of Washington, Seattle, WA 98101, USA., Buckner JH; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.; Department of Immunology, University of Washington, Seattle, WA 98101, USA.; Department of Medicine, University of Washington, Seattle, WA 98101, USA.
Source: Science translational medicine [Sci Transl Med] 2022 Oct 05; Vol. 14 (665), pp. eabn1716. Date of Electronic Publication: 2022 Oct 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36197963
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Pancreatic islet-specific engineered T<subscript>regs</subscript> exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Yang+SJ%22">Yang SJ</searchLink>; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Singh+AK%22">Singh AK</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Drow+T%22">Drow T</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Tappen+T%22">Tappen T</searchLink>; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Honaker+Y%22">Honaker Y</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Barahmand-Pour-Whitman+F%22">Barahmand-Pour-Whitman F</searchLink>; Center for Systems Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Linsley+PS%22">Linsley PS</searchLink>; Center for Systems Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Cerosaletti+K%22">Cerosaletti K</searchLink>; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Mauk+K%22">Mauk K</searchLink>; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Xiang+Y%22">Xiang Y</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Smith+J%22">Smith J</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Mortensen+E%22">Mortensen E</searchLink>; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Cook+PJ%22">Cook PJ</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Sommer+K%22">Sommer K</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Khan+I%22">Khan I</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Liggitt+D%22">Liggitt D</searchLink>; Department of Comparative Medicine, University of Washington, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Rawlings+DJ%22">Rawlings DJ</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA.; Department of Immunology, University of Washington, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Buckner+JH%22">Buckner JH</searchLink>; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.; Department of Immunology, University of Washington, Seattle, WA 98101, USA.; Department of Medicine, University of Washington, Seattle, WA 98101, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2022 Oct 05; Vol. 14 (665), pp. eabn1716. <i>Date of Electronic Publication: </i>2022 Oct 05.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36197963
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/scitranslmed.abn1716
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: eabn1716
    Titles:
      – TitleFull: Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Yang SJ
      – PersonEntity:
          Name:
            NameFull: Singh AK
      – PersonEntity:
          Name:
            NameFull: Drow T
      – PersonEntity:
          Name:
            NameFull: Tappen T
      – PersonEntity:
          Name:
            NameFull: Honaker Y
      – PersonEntity:
          Name:
            NameFull: Barahmand-Pour-Whitman F
      – PersonEntity:
          Name:
            NameFull: Linsley PS
      – PersonEntity:
          Name:
            NameFull: Cerosaletti K
      – PersonEntity:
          Name:
            NameFull: Mauk K
      – PersonEntity:
          Name:
            NameFull: Xiang Y
      – PersonEntity:
          Name:
            NameFull: Smith J
      – PersonEntity:
          Name:
            NameFull: Mortensen E
      – PersonEntity:
          Name:
            NameFull: Cook PJ
      – PersonEntity:
          Name:
            NameFull: Sommer K
      – PersonEntity:
          Name:
            NameFull: Khan I
      – PersonEntity:
          Name:
            NameFull: Liggitt D
      – PersonEntity:
          Name:
            NameFull: Rawlings DJ
      – PersonEntity:
          Name:
            NameFull: Buckner JH
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 05
              M: 10
              Text: 2022 Oct 05
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1946-6242
          Numbering:
            – Type: volume
              Value: 14
            – Type: issue
              Value: 665
          Titles:
            – TitleFull: Science translational medicine
              Type: main
ResultId 1