Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors.
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| Title: | Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors. |
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| Authors: | Asberry AM; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.; Purdue University Interdisciplinary Life Sciences Graduate Program, Purdue University, West Lafayette, Indiana 47907, United States., Cai X; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States., Deng X; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States., Santiago U; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Liu S; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States.; The Indiana University Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, Indiana 46202, United States., Sims HS; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States., Liang W; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States., Xu X; Department of Biological Sciences, Purdue University, 240 S Martin Jischke Drive, West Lafayette, Indiana 47907, United States., Wan J; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States.; The Indiana University Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, Indiana 46202, United States.; The Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States., Jiang W; Department of Biological Sciences, Purdue University, 240 S Martin Jischke Drive, West Lafayette, Indiana 47907, United States.; Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States., Camacho CJ; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Dai M; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.; Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Hu CD; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.; Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2022 Oct 27; Vol. 65 (20), pp. 13793-13812. Date of Electronic Publication: 2022 Oct 07. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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