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Longitudinal Effects of Combination Antiretroviral Therapy on Cognition and Neuroimaging Biomarkers in Treatment-Naive People With HIV.

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Title: Longitudinal Effects of Combination Antiretroviral Therapy on Cognition and Neuroimaging Biomarkers in Treatment-Naive People With HIV.
Authors: Weber MT; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY. miriam_weber@urmc.rochester.edu., Finkelstein A; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Uddin MN; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Reddy EA; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Arduino RC; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Wang L; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Tivarus ME; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Zhong J; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Qiu X; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY., Schifitto G; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.
Source: Neurology [Neurology] 2022 Sep 06; Vol. 99 (10), pp. e1045-e1055. Date of Electronic Publication: 2022 Jun 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
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  Data: Longitudinal Effects of Combination Antiretroviral Therapy on Cognition and Neuroimaging Biomarkers in Treatment-Naive People With HIV.
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  Data: <searchLink fieldCode="AU" term="%22Weber+MT%22">Weber MT</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY. miriam_weber@urmc.rochester.edu.<br /><searchLink fieldCode="AU" term="%22Finkelstein+A%22">Finkelstein A</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Uddin+MN%22">Uddin MN</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Reddy+EA%22">Reddy EA</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Arduino+RC%22">Arduino RC</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Tivarus+ME%22">Tivarus ME</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Zhong+J%22">Zhong J</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Qiu+X%22">Qiu X</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Schifitto+G%22">Schifitto G</searchLink>; From the Departments of Neurology (M.T.W., M.N.U., G.S.), Obstetrics and Gynecology (M.T.W.), and Biomedical Engineering (A.F., J.Z.), University of Rochester, NY; Department of Infectious Disease (E.A.R.), SUNY Upstate Medical Center, Syracuse, NY; Department of Internal Medicine (R.C.A.), McGovern Medical School at The University of Texas Health Science Center at Houston; Departments of Biostatistics and Computational Biology (L.W., X.Q., G.S.), Imaging Sciences (M.E.T., J.Z.), and Neuroscience (M.E.T.), University of Rochester Medical Center; and Department of Physics and Astronomy (J.Z.), University of Rochester, NY.
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