Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
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| Title: | Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity. |
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| Authors: | Minnie SA; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Waltner OG; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Ensbey KS; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Nemychenkov NS; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Schmidt CR; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Bhise SS; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Legg SRW; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Campoy G; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Samson LD; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Kuns RD; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Zhou T; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA., Huck JD; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA., Vuckovic S; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Zamora D; Department of Medicine, University of Washington, Seattle, WA 98109, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Yeh A; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA., Spencer A; Australian Center for Blood Diseases, Monash University/the Alfred Hospital, Melbourne, VIC 3004, Australia.; Malignant Haematology and Stem Cell Transplantation, the Alfred Hospital, Melbourne, VIC 3004, Australia.; Department of Clinical Haematology, Monash University, Melbourne, VIC 3800, Australia., Koyama M; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Markey KA; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA., Lane SW; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Boeckh M; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Ring AM; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA., Furlan SN; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA., Hill GR; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA. |
| Source: | Science immunology [Sci Immunol] 2022 Oct 21; Vol. 7 (76), pp. eabo3420. Date of Electronic Publication: 2022 Oct 14. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2470-9468 |
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| DOI: | 10.1126/sciimmunol.abo3420 |