Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.

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Title: Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
Authors: Minnie SA; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Waltner OG; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Ensbey KS; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Nemychenkov NS; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Schmidt CR; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Bhise SS; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Legg SRW; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Campoy G; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Samson LD; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Kuns RD; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Zhou T; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA., Huck JD; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA., Vuckovic S; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Zamora D; Department of Medicine, University of Washington, Seattle, WA 98109, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Yeh A; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA., Spencer A; Australian Center for Blood Diseases, Monash University/the Alfred Hospital, Melbourne, VIC 3004, Australia.; Malignant Haematology and Stem Cell Transplantation, the Alfred Hospital, Melbourne, VIC 3004, Australia.; Department of Clinical Haematology, Monash University, Melbourne, VIC 3800, Australia., Koyama M; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Markey KA; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA., Lane SW; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Boeckh M; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Ring AM; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA., Furlan SN; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA., Hill GR; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA.
Source: Science immunology [Sci Immunol] 2022 Oct 21; Vol. 7 (76), pp. eabo3420. Date of Electronic Publication: 2022 Oct 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
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  Data: Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
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  Data: <searchLink fieldCode="AU" term="%22Minnie+SA%22">Minnie SA</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Waltner+OG%22">Waltner OG</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Ensbey+KS%22">Ensbey KS</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Nemychenkov+NS%22">Nemychenkov NS</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+CR%22">Schmidt CR</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Bhise+SS%22">Bhise SS</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Legg+SRW%22">Legg SRW</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Campoy+G%22">Campoy G</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Samson+LD%22">Samson LD</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Kuns+RD%22">Kuns RD</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Zhou+T%22">Zhou T</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.<br /><searchLink fieldCode="AU" term="%22Huck+JD%22">Huck JD</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.<br /><searchLink fieldCode="AU" term="%22Vuckovic+S%22">Vuckovic S</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Zamora+D%22">Zamora D</searchLink>; Department of Medicine, University of Washington, Seattle, WA 98109, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Yeh+A%22">Yeh A</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Spencer+A%22">Spencer A</searchLink>; Australian Center for Blood Diseases, Monash University/the Alfred Hospital, Melbourne, VIC 3004, Australia.; Malignant Haematology and Stem Cell Transplantation, the Alfred Hospital, Melbourne, VIC 3004, Australia.; Department of Clinical Haematology, Monash University, Melbourne, VIC 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Koyama+M%22">Koyama M</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Markey+KA%22">Markey KA</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Lane+SW%22">Lane SW</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Boeckh+M%22">Boeckh M</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Ring+AM%22">Ring AM</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.<br /><searchLink fieldCode="AU" term="%22Furlan+SN%22">Furlan SN</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA.<br /><searchLink fieldCode="AU" term="%22Hill+GR%22">Hill GR</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Medicine, University of Washington, Seattle, WA 98109, USA.
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  Data: <searchLink fieldCode="JN" term="%22101688624%22">Science immunology</searchLink> [Sci Immunol] 2022 Oct 21; Vol. 7 (76), pp. eabo3420. <i>Date of Electronic Publication: </i>2022 Oct 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101688624 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2470-9468 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224709468%22">24709468 </searchLink><i>NLM ISO Abbreviation: </i>Sci Immunol <i>Subsets: </i>MEDLINE
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