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New quinazolinone-based derivatives as DHFR/EGFR-TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity.

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Title: New quinazolinone-based derivatives as DHFR/EGFR-TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity.
Authors: El-Gazzar YI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt., Ghaiad HR; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt., El Kerdawy AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.; Department of Pharmaceutical Chemistry, School of Pharmacy, Newgiza University (NGU), Cairo, Egypt., George RF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Georgey HH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Drug Technology, Egyptian Chinese University, Cairo, Egypt., Youssef KM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt., El-Subbagh HI; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2023 Jan; Vol. 356 (1), pp. e2200417. Date of Electronic Publication: 2022 Oct 18.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: New quinazolinone-based derivatives as DHFR/EGFR-TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity.
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  Data: <searchLink fieldCode="AU" term="%22El-Gazzar+YI%22">El-Gazzar YI</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Ghaiad+HR%22">Ghaiad HR</searchLink>; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22El+Kerdawy+AM%22">El Kerdawy AM</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.; Department of Pharmaceutical Chemistry, School of Pharmacy, Newgiza University (NGU), Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22George+RF%22">George RF</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Georgey+HH%22">Georgey HH</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Drug Technology, Egyptian Chinese University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Youssef+KM%22">Youssef KM</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Subbagh+HI%22">El-Subbagh HI</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
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        Value: 10.1002/ardp.202200417
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      – TitleFull: New quinazolinone-based derivatives as DHFR/EGFR-TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity.
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              Text: 2023 Jan
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