Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
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| Title: | Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication. |
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| Authors: | Yaron TM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine/Memorial Sloan Kettering Cancer Center/Rockefeller University, New York, NY 10021, USA., Heaton BE; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Levy TM; Cell Signaling Technology, Danvers, MA 01923, USA., Johnson JL; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Jordan TX; Grossman School of Medicine, New York University, New York, NY 10016, USA., Cohen BM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Kerelsky A; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Lin TY; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Liberatore KM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Bulaon DK; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Van Nest SJ; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Koundouros N; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA., Kastenhuber ER; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Mercadante MN; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Shobana-Ganesh K; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., He L; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Schwartz RE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Chen S; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA., Weinstein H; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA., Elemento O; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA., Piskounova E; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Dermatology, Weill Cornell Medicine, New York, NY 10065, USA., Nilsson-Payant BE; Grossman School of Medicine, New York University, New York, NY 10016, USA., Lee G; Department of Microbiology and Molecular Genetics, Chao Family Comprehensive Cancer Center, University of California, Irvine School of Medicine, Irvine, CA 92868, USA., Trimarco JD; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Burke KN; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Hamele CE; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Chaparian RR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Harding AT; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Tata A; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Zhu X; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Tata PR; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Smith CM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Possemato AP; Cell Signaling Technology, Danvers, MA 01923, USA., Tkachev SL; Cell Signaling Technology, Danvers, MA 01923, USA., Hornbeck PV; Cell Signaling Technology, Danvers, MA 01923, USA., Beausoleil SA; Cell Signaling Technology, Danvers, MA 01923, USA., Anand SK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Aguet F; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Getz G; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.; Cancer Center and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Davidson AD; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., Heesom K; Proteomics Facility, University of Bristol, Bristol BS8 1TD, UK., Kavanagh-Williamson M; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., Matthews DA; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., tenOever BR; Grossman School of Medicine, New York University, New York, NY 10016, USA., Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Blenis J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA.; Department of Biochemistry, Weill Cornell Medicine, New York, NY 10065, USA., Heaton NS; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC 27710, USA. |
| Source: | Science signaling [Sci Signal] 2022 Oct 25; Vol. 15 (757), pp. eabm0808. Date of Electronic Publication: 2022 Oct 25. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36282911 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yaron+TM%22">Yaron TM</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine/Memorial Sloan Kettering Cancer Center/Rockefeller University, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Heaton+BE%22">Heaton BE</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Levy+TM%22">Levy TM</searchLink>; Cell Signaling Technology, Danvers, MA 01923, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+JL%22">Johnson JL</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Jordan+TX%22">Jordan TX</searchLink>; Grossman School of Medicine, New York University, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+BM%22">Cohen BM</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Kerelsky+A%22">Kerelsky A</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Lin+TY%22">Lin TY</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Liberatore+KM%22">Liberatore KM</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Bulaon+DK%22">Bulaon DK</searchLink>; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Van+Nest+SJ%22">Van Nest SJ</searchLink>; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Koundouros+N%22">Koundouros N</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Kastenhuber+ER%22">Kastenhuber ER</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Mercadante+MN%22">Mercadante MN</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Shobana-Ganesh+K%22">Shobana-Ganesh K</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22He+L%22">He L</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Schwartz+RE%22">Schwartz RE</searchLink>; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Weinstein+H%22">Weinstein H</searchLink>; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Elemento+O%22">Elemento O</searchLink>; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Piskounova+E%22">Piskounova E</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Dermatology, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Nilsson-Payant+BE%22">Nilsson-Payant BE</searchLink>; Grossman School of Medicine, New York University, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Lee+G%22">Lee G</searchLink>; Department of Microbiology and Molecular Genetics, Chao Family Comprehensive Cancer Center, University of California, Irvine School of Medicine, Irvine, CA 92868, USA.<br /><searchLink fieldCode="AU" term="%22Trimarco+JD%22">Trimarco JD</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Burke+KN%22">Burke KN</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Hamele+CE%22">Hamele CE</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Chaparian+RR%22">Chaparian RR</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Harding+AT%22">Harding AT</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Tata+A%22">Tata A</searchLink>; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Tata+PR%22">Tata PR</searchLink>; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Smith+CM%22">Smith CM</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Possemato+AP%22">Possemato AP</searchLink>; Cell Signaling Technology, Danvers, MA 01923, USA.<br /><searchLink fieldCode="AU" term="%22Tkachev+SL%22">Tkachev SL</searchLink>; Cell Signaling Technology, Danvers, MA 01923, USA.<br /><searchLink fieldCode="AU" term="%22Hornbeck+PV%22">Hornbeck PV</searchLink>; Cell Signaling Technology, Danvers, MA 01923, USA.<br /><searchLink fieldCode="AU" term="%22Beausoleil+SA%22">Beausoleil SA</searchLink>; Cell Signaling Technology, Danvers, MA 01923, USA.<br /><searchLink fieldCode="AU" term="%22Anand+SK%22">Anand SK</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Aguet+F%22">Aguet F</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Getz+G%22">Getz G</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.; Cancer Center and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Davidson+AD%22">Davidson AD</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22Heesom+K%22">Heesom K</searchLink>; Proteomics Facility, University of Bristol, Bristol BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22Kavanagh-Williamson+M%22">Kavanagh-Williamson M</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22Matthews+DA%22">Matthews DA</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22tenOever+BR%22">tenOever BR</searchLink>; Grossman School of Medicine, New York University, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Cantley+LC%22">Cantley LC</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Blenis+J%22">Blenis J</searchLink>; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA.; Department of Biochemistry, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Heaton+NS%22">Heaton NS</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; 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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/scisignal.abm0808 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eabm0808 Titles: – TitleFull: Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yaron TM – PersonEntity: Name: NameFull: Heaton BE – PersonEntity: Name: NameFull: Levy TM – PersonEntity: Name: NameFull: Johnson JL – PersonEntity: Name: NameFull: Jordan TX – PersonEntity: Name: NameFull: Cohen BM – PersonEntity: Name: NameFull: Kerelsky A – PersonEntity: Name: NameFull: Lin TY – PersonEntity: Name: NameFull: Liberatore KM – PersonEntity: Name: NameFull: Bulaon DK – PersonEntity: Name: NameFull: Van Nest SJ – PersonEntity: Name: NameFull: Koundouros N – PersonEntity: Name: NameFull: Kastenhuber ER – PersonEntity: Name: NameFull: Mercadante MN – PersonEntity: Name: NameFull: Shobana-Ganesh K – PersonEntity: Name: NameFull: He L – PersonEntity: Name: NameFull: Schwartz RE – PersonEntity: Name: NameFull: Chen S – PersonEntity: Name: NameFull: Weinstein H – PersonEntity: Name: NameFull: Elemento O – PersonEntity: Name: NameFull: Piskounova E – PersonEntity: Name: NameFull: Nilsson-Payant BE – PersonEntity: Name: NameFull: Lee G – PersonEntity: Name: NameFull: Trimarco JD – PersonEntity: Name: NameFull: Burke KN – PersonEntity: Name: NameFull: Hamele CE – PersonEntity: Name: NameFull: Chaparian RR – PersonEntity: Name: NameFull: Harding AT – PersonEntity: Name: NameFull: Tata A – PersonEntity: Name: NameFull: Zhu X – PersonEntity: Name: NameFull: Tata PR – PersonEntity: Name: NameFull: Smith CM – PersonEntity: Name: NameFull: Possemato AP – PersonEntity: Name: NameFull: Tkachev SL – PersonEntity: Name: NameFull: Hornbeck PV – PersonEntity: Name: NameFull: Beausoleil SA – PersonEntity: Name: NameFull: Anand SK – PersonEntity: Name: NameFull: Aguet F – PersonEntity: Name: NameFull: Getz G – PersonEntity: Name: NameFull: Davidson AD – PersonEntity: Name: NameFull: Heesom K – PersonEntity: Name: NameFull: Kavanagh-Williamson M – PersonEntity: Name: NameFull: Matthews DA – PersonEntity: Name: NameFull: tenOever BR – PersonEntity: Name: NameFull: Cantley LC – PersonEntity: Name: NameFull: Blenis J – PersonEntity: Name: NameFull: Heaton NS IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 10 Text: 2022 Oct 25 Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1937-9145 Numbering: – Type: volume Value: 15 – Type: issue Value: 757 Titles: – TitleFull: Science signaling Type: main |
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