Synthesis and Anti-Inflammatory Activity of 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-Derived NRF2 Activators.
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| Title: | Synthesis and Anti-Inflammatory Activity of 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-Derived NRF2 Activators. |
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| Authors: | Mak KK; Pharmaceutical Chemistry Department, International Medical University, 126 Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; Centre of Excellence for Bioactive Molecules and Drug Delivery, Institute for Research, Development, and Innovation (IRDI), International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; School of Postgraduate Studies, International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia., Shiming Z; School of Postgraduate Studies, International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia., Epemolu O; Principal research scientist- in vitro/in vivo DMPK, Charles River Laboratories Edinburgh Ltd, Tranent, East Lothian, Scotland, UK., Dinkova-Kostova AT; School of Medicine, Jacqui Wood Cancer Centre, University of Dundee, Dundee, Scotland, UK.; Departments of Medicine and Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MA, USA., Wells G; UCL School of Pharmacy, University College London, London, WC1N 1AX, UK., Gazaryan IG; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia.; Department of Chemical Enzymology, M.V. Lomonosov Moscow State University, Moscow, Russia.; Department of Chemistry and Physical Sciences, Pace University, Pleasantville, NY, USA., Sakirolla R; Department of Chemistry, Central University of Karnataka, Gulbarga, Karnataka, India., Mohd Z; Pharmaceutical Chemistry Department, International Medical University, 126 Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; Centre of Excellence for Bioactive Molecules and Drug Delivery, Institute for Research, Development, and Innovation (IRDI), International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia., Pichika MR; Pharmaceutical Chemistry Department, International Medical University, 126 Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.; Centre of Excellence for Bioactive Molecules and Drug Delivery, Institute for Research, Development, and Innovation (IRDI), International Medical University, 126 Jalan Jalil Perkasa 19 Bukit Jalil, 57000, Kuala Lumpur, Malaysia. |
| Source: | ChemistryOpen [ChemistryOpen] 2022 Oct; Vol. 11 (10), pp. e202200181. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101594811 Publication Model: Print Cited Medium: Internet ISSN: 2191-1363 (Electronic) Linking ISSN: 21911363 NLM ISO Abbreviation: ChemistryOpen Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2191-1363 |
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| DOI: | 10.1002/open.202200181 |