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Small molecule inhibitor against onco-mucins disrupts Src/FosL1 axis to enhance gemcitabine efficacy in pancreatic ductal adenocarcinoma.

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Title: Small molecule inhibitor against onco-mucins disrupts Src/FosL1 axis to enhance gemcitabine efficacy in pancreatic ductal adenocarcinoma.
Authors: Zhang C; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Department of Surgical Oncology, University of Nebraska Medical Center, Omaha, NE, USA., Atri P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Nallasamy P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Parte S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Rauth S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Nimmakayala RK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Marimuthu S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Chirravuri-Venkata R; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Bhatia R; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Halder S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Shah A; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Cox JL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA., Smith L; Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, USA., Kumar S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Foster JM; Department of Surgical Oncology, University of Nebraska Medical Center, Omaha, NE, USA., Kukreja RC; Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, 23298-0204, USA., Seshacharyulu P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Ponnusamy MP; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Disease, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: mpalanim@unmc.edu., Batra SK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Disease, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: sbatra@unmc.edu.
Source: Cancer letters [Cancer Lett] 2022 Dec 28; Vol. 551, pp. 215922. Date of Electronic Publication: 2022 Sep 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Small molecule inhibitor against onco-mucins disrupts Src/FosL1 axis to enhance gemcitabine efficacy in pancreatic ductal adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Department of Surgical Oncology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Atri+P%22">Atri P</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Nallasamy+P%22">Nallasamy P</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Parte+S%22">Parte S</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Rauth+S%22">Rauth S</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Nimmakayala+RK%22">Nimmakayala RK</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Marimuthu+S%22">Marimuthu S</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Chirravuri-Venkata+R%22">Chirravuri-Venkata R</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Bhatia+R%22">Bhatia R</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Halder+S%22">Halder S</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Shah+A%22">Shah A</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Cox+JL%22">Cox JL</searchLink>; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Smith+L%22">Smith L</searchLink>; Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+S%22">Kumar S</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Foster+JM%22">Foster JM</searchLink>; Department of Surgical Oncology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Kukreja+RC%22">Kukreja RC</searchLink>; Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, 23298-0204, USA.<br /><searchLink fieldCode="AU" term="%22Seshacharyulu+P%22">Seshacharyulu P</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Ponnusamy+MP%22">Ponnusamy MP</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Disease, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: mpalanim@unmc.edu.<br /><searchLink fieldCode="AU" term="%22Batra+SK%22">Batra SK</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Disease, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: sbatra@unmc.edu.
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  Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2022 Dec 28; Vol. 551, pp. 215922. <i>Date of Electronic Publication: </i>2022 Sep 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ireland%22">Elsevier Science Ireland </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7600053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043835%22">03043835 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Lett <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.canlet.2022.215922
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