Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy.
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| Title: | Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy. |
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| Authors: | Oh YM; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Lee SW; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Kim WK; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Chen S; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Church VA; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Cates K; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Li T; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA., Zhang B; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA., Dolle RE; Department of Biochemistry, Washington University School of Medicine, St. Louis, MO, USA., Dahiya S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Pak SC; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Silverman GA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Perlmutter DH; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Yoo AS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA. yooa@wustl.edu.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA. yooa@wustl.edu. |
| Source: | Nature neuroscience [Nat Neurosci] 2022 Nov; Vol. 25 (11), pp. 1420-1433. Date of Electronic Publication: 2022 Oct 27. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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