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Fragment screening at AstraZeneca: developing the next generation biophysics fragment set.

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Title: Fragment screening at AstraZeneca: developing the next generation biophysics fragment set.
Authors: Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com., Börjesson U; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Bostock MJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Cuff J; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Edfeldt F; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Embrey KJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Eriksson PO; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Gohlke A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Gunnarson A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Lainchbury M; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com., Milbradt AG; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Moore R; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Rawlins PB; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Sinclair I; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Stubbs C; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Storer RI; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com.
Source: RSC medicinal chemistry [RSC Med Chem] 2022 Jul 04; Vol. 13 (9), pp. 1052-1057. Date of Electronic Publication: 2022 Jul 04 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2632-8682
DOI:10.1039/d2md00154c