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Fragment screening at AstraZeneca: developing the next generation biophysics fragment set.

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Title: Fragment screening at AstraZeneca: developing the next generation biophysics fragment set.
Authors: Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com., Börjesson U; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Bostock MJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Cuff J; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Edfeldt F; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Embrey KJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Eriksson PO; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Gohlke A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Gunnarson A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Lainchbury M; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com., Milbradt AG; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Moore R; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Rawlins PB; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Sinclair I; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Stubbs C; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Storer RI; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com.
Source: RSC medicinal chemistry [RSC Med Chem] 2022 Jul 04; Vol. 13 (9), pp. 1052-1057. Date of Electronic Publication: 2022 Jul 04 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem Subsets: PubMed not MEDLINE
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  Data: Fragment screening at AstraZeneca: developing the next generation biophysics fragment set.
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  Data: <searchLink fieldCode="AU" term="%22Lucas+SCC%22">Lucas SCC</searchLink>; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com.<br /><searchLink fieldCode="AU" term="%22Börjesson+U%22">Börjesson U</searchLink>; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden.<br /><searchLink fieldCode="AU" term="%22Bostock+MJ%22">Bostock MJ</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK.<br /><searchLink fieldCode="AU" term="%22Cuff+J%22">Cuff J</searchLink>; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK.<br /><searchLink fieldCode="AU" term="%22Edfeldt+F%22">Edfeldt F</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden.<br /><searchLink fieldCode="AU" term="%22Embrey+KJ%22">Embrey KJ</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK.<br /><searchLink fieldCode="AU" term="%22Eriksson+PO%22">Eriksson PO</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden.<br /><searchLink fieldCode="AU" term="%22Gohlke+A%22">Gohlke A</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK.<br /><searchLink fieldCode="AU" term="%22Gunnarson+A%22">Gunnarson A</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden.<br /><searchLink fieldCode="AU" term="%22Lainchbury+M%22">Lainchbury M</searchLink>; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com.<br /><searchLink fieldCode="AU" term="%22Milbradt+AG%22">Milbradt AG</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK.<br /><searchLink fieldCode="AU" term="%22Moore+R%22">Moore R</searchLink>; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Alderley Park UK.<br /><searchLink fieldCode="AU" term="%22Rawlins+PB%22">Rawlins PB</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK.<br /><searchLink fieldCode="AU" term="%22Sinclair+I%22">Sinclair I</searchLink>; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK.<br /><searchLink fieldCode="AU" term="%22Stubbs+C%22">Stubbs C</searchLink>; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK.<br /><searchLink fieldCode="AU" term="%22Storer+RI%22">Storer RI</searchLink>; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com.
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