Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs.
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| Title: | Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs. |
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| Authors: | Smith DH; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Axonova Medical LLC, Philadelphia, PA, USA., Burrell JC; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA., Browne KD; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Katiyar KS; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Axonova Medical LLC, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Ezra MI; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Dutton JL; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Morand JP; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Struzyna LA; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA., Laimo FA; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Chen HI; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Wolf JA; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Kaplan HM; New Jersey Center for Biomaterials, Rutgers University, Piscataway, NJ, USA., Rosen JM; Division of Plastic Surgery, Dartmouth Hitchcock Medical Center, Dartmouth College, Lebanon, NH, USA., Ledebur HC; Axonova Medical LLC, Philadelphia, PA, USA., Zager EL; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ali ZS; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Cullen DK; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Axonova Medical LLC, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. |
| Source: | Science advances [Sci Adv] 2022 Nov 04; Vol. 8 (44), pp. eabm3291. Date of Electronic Publication: 2022 Nov 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE; PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36332027 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Smith+DH%22">Smith DH</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Axonova Medical LLC, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Burrell+JC%22">Burrell JC</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Browne+KD%22">Browne KD</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Katiyar+KS%22">Katiyar KS</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Axonova Medical LLC, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ezra+MI%22">Ezra MI</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dutton+JL%22">Dutton JL</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Morand+JP%22">Morand JP</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Struzyna+LA%22">Struzyna LA</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Laimo+FA%22">Laimo FA</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+HI%22">Chen HI</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wolf+JA%22">Wolf JA</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kaplan+HM%22">Kaplan HM</searchLink>; New Jersey Center for Biomaterials, Rutgers University, Piscataway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Rosen+JM%22">Rosen JM</searchLink>; Division of Plastic Surgery, Dartmouth Hitchcock Medical Center, Dartmouth College, Lebanon, NH, USA.<br /><searchLink fieldCode="AU" term="%22Ledebur+HC%22">Ledebur HC</searchLink>; Axonova Medical LLC, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zager+EL%22">Zager EL</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ali+ZS%22">Ali ZS</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Cullen+DK%22">Cullen DK</searchLink>; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Axonova Medical LLC, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2022 Nov 04; Vol. 8 (44), pp. eabm3291. <i>Date of Electronic Publication: </i>2022 Nov 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101653440 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2375-2548 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223752548%22">23752548 </searchLink><i>NLM ISO Abbreviation: </i>Sci Adv <i>Subsets: </i>MEDLINE; PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36332027 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/sciadv.abm3291 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eabm3291 Titles: – TitleFull: Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Smith DH – PersonEntity: Name: NameFull: Burrell JC – PersonEntity: Name: NameFull: Browne KD – PersonEntity: Name: NameFull: Katiyar KS – PersonEntity: Name: NameFull: Ezra MI – PersonEntity: Name: NameFull: Dutton JL – PersonEntity: Name: NameFull: Morand JP – PersonEntity: Name: NameFull: Struzyna LA – PersonEntity: Name: NameFull: Laimo FA – PersonEntity: Name: NameFull: Chen HI – PersonEntity: Name: NameFull: Wolf JA – PersonEntity: Name: NameFull: Kaplan HM – PersonEntity: Name: NameFull: Rosen JM – PersonEntity: Name: NameFull: Ledebur HC – PersonEntity: Name: NameFull: Zager EL – PersonEntity: Name: NameFull: Ali ZS – PersonEntity: Name: NameFull: Cullen DK IsPartOfRelationships: – BibEntity: Dates: – D: 04 M: 11 Text: 2022 Nov 04 Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 2375-2548 Numbering: – Type: volume Value: 8 – Type: issue Value: 44 Titles: – TitleFull: Science advances Type: main |
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