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Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection.

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Title: Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection.
Authors: Yoshimoto T; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Kittaka M; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Doan AAP; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Urata R; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Prideaux M; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Rojas RE; Janssen Biopharma Inc, Brisbane, CA, 94005-1809, USA., Harding CV; Department of Pathology, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA., Henry Boom W; Department of Pathology, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA.; Department of Medicine, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA.; Department of Molecular Biology and Microbiology, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA., Bonewald LF; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Greenfield EM; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA., Ueki Y; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA. uekiy@iu.edu.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA. uekiy@iu.edu.
Source: Nature communications [Nat Commun] 2022 Nov 04; Vol. 13 (1), pp. 6648. Date of Electronic Publication: 2022 Nov 04.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yoshimoto+T%22">Yoshimoto T</searchLink>; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Kittaka+M%22">Kittaka M</searchLink>; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Doan+AAP%22">Doan AAP</searchLink>; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Urata+R%22">Urata R</searchLink>; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Prideaux+M%22">Prideaux M</searchLink>; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Rojas+RE%22">Rojas RE</searchLink>; Janssen Biopharma Inc, Brisbane, CA, 94005-1809, USA.<br /><searchLink fieldCode="AU" term="%22Harding+CV%22">Harding CV</searchLink>; Department of Pathology, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA.<br /><searchLink fieldCode="AU" term="%22Henry+Boom+W%22">Henry Boom W</searchLink>; Department of Pathology, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA.; Department of Medicine, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA.; Department of Molecular Biology and Microbiology, Case Western Reserve University & University Hospitals Cleveland Medical Center, Cleveland, OH, 44106-4960, USA.<br /><searchLink fieldCode="AU" term="%22Bonewald+LF%22">Bonewald LF</searchLink>; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Greenfield+EM%22">Greenfield EM</searchLink>; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA.<br /><searchLink fieldCode="AU" term="%22Ueki+Y%22">Ueki Y</searchLink>; Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN, 46202-5126, USA. uekiy@iu.edu.; Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, 46202-5126, USA. uekiy@iu.edu.
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