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Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress.

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Title: Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress.
Authors: Delfinis LJ; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada., Bellissimo CA; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada., Gandhi S; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada., DiBenedetto SN; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada., Garibotti MC; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada., Thuhan AK; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada., Tsitkanou S; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, Arkansas, USA., Rosa-Caldwell ME; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, Arkansas, USA., Rahman FA; Department of Kinesiology and Health Sciences, Faculty of Health, University of Waterloo, Waterloo, Ontario, Canada., Cheng AJ; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada., Wiggs MP; Mooney Lab for Exercise, Nutrition, and Biochemistry, Department of Health, Human Performance, and Recreation, Baylor University, Waco, Texas, USA., Schlattner U; Laboratory of Fundamental and Applied Bioenergetics, University Grenoble Alpes and INSERM U1055, Grenoble, France, and Institut Universitaire de France, Paris, France., Quadrilatero J; Department of Kinesiology and Health Sciences, Faculty of Health, University of Waterloo, Waterloo, Ontario, Canada., Greene NP; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, Arkansas, USA., Perry CG; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.
Source: JCI insight [JCI Insight] 2022 Dec 22; Vol. 7 (24). Date of Electronic Publication: 2022 Dec 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress.
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  Data: <searchLink fieldCode="AU" term="%22Delfinis+LJ%22">Delfinis LJ</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Bellissimo+CA%22">Bellissimo CA</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Gandhi+S%22">Gandhi S</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22DiBenedetto+SN%22">DiBenedetto SN</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Garibotti+MC%22">Garibotti MC</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Thuhan+AK%22">Thuhan AK</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Tsitkanou+S%22">Tsitkanou S</searchLink>; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, Arkansas, USA.<br /><searchLink fieldCode="AU" term="%22Rosa-Caldwell+ME%22">Rosa-Caldwell ME</searchLink>; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, Arkansas, USA.<br /><searchLink fieldCode="AU" term="%22Rahman+FA%22">Rahman FA</searchLink>; Department of Kinesiology and Health Sciences, Faculty of Health, University of Waterloo, Waterloo, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Cheng+AJ%22">Cheng AJ</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Wiggs+MP%22">Wiggs MP</searchLink>; Mooney Lab for Exercise, Nutrition, and Biochemistry, Department of Health, Human Performance, and Recreation, Baylor University, Waco, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Schlattner+U%22">Schlattner U</searchLink>; Laboratory of Fundamental and Applied Bioenergetics, University Grenoble Alpes and INSERM U1055, Grenoble, France, and Institut Universitaire de France, Paris, France.<br /><searchLink fieldCode="AU" term="%22Quadrilatero+J%22">Quadrilatero J</searchLink>; Department of Kinesiology and Health Sciences, Faculty of Health, University of Waterloo, Waterloo, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Greene+NP%22">Greene NP</searchLink>; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, Arkansas, USA.<br /><searchLink fieldCode="AU" term="%22Perry+CG%22">Perry CG</searchLink>; Muscle Health Research Centre, School of Kinesiology, Faculty of Health, York University, Toronto, Ontario, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2022 Dec 22; Vol. 7 (24). <i>Date of Electronic Publication: </i>2022 Dec 22.
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