Effect of Roflumilast Cream (ARQ-151) on Itch and Itch-Related Sleep Loss in Adults with Chronic Plaque Psoriasis: Patient-Reported Itch Outcomes of a Phase 2b Trial.

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Title: Effect of Roflumilast Cream (ARQ-151) on Itch and Itch-Related Sleep Loss in Adults with Chronic Plaque Psoriasis: Patient-Reported Itch Outcomes of a Phase 2b Trial.
Authors: Stein Gold L; Henry Ford Medical Center, New Center One Dermatology Research, 7th Floor, 3031 West Grand Boulevard, Detroit, MI, 48202, USA. lstein1@hfhs.org., Alonso-Llamazares J; Driven Research LLC, Coral Gables, FL, USA., Draelos ZD; Dermatology Consulting Services, High Point, NC, USA., Gooderham MJ; SKiN Centre for Dermatology, Probity Medical Research and Queen's University, Peterborough, ON, Canada., Kempers SE; Minnesota Clinical Study Center, New Brighton, MN, USA., Kircik LH; Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Indiana Medical Center, Indianapolis, IN, USA.; Physicians Skin Care, PLLC, Louisville, KY, USA.; Skin Sciences, PLLC, Louisville, KY, USA., Lebwohl MG; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Papp KA; Probity Medical Research and K Papp Clinical Research, Waterloo, ON, Canada., Pariser DM; Department of Dermatology, Eastern Virginia Medical School and Virginia Clinical Research, Inc., Norfolk, VA, USA., Toth DP; XLR8 Medical Research, Probity Medical Research, Windsor, ON, Canada., Yosipovitch G; University of Miami, Miami, FL, USA., Higham RC; Arcutis Biotherapeutics, Inc., Westlake Village, CA, USA., Feng A; Arcutis Biotherapeutics, Inc., Westlake Village, CA, USA., Berk DR; Arcutis Biotherapeutics, Inc., Westlake Village, CA, USA.
Source: American journal of clinical dermatology [Am J Clin Dermatol] 2023 Mar; Vol. 24 (2), pp. 305-313. Date of Electronic Publication: 2022 Nov 12.
Publication Type: Randomized Controlled Trial; Journal Article
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 100895290 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1888 (Electronic) Linking ISSN: 11750561 NLM ISO Abbreviation: Am J Clin Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of Roflumilast Cream (ARQ-151) on Itch and Itch-Related Sleep Loss in Adults with Chronic Plaque Psoriasis: Patient-Reported Itch Outcomes of a Phase 2b Trial.
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  Data: <searchLink fieldCode="AU" term="%22Stein+Gold+L%22">Stein Gold L</searchLink>; Henry Ford Medical Center, New Center One Dermatology Research, 7th Floor, 3031 West Grand Boulevard, Detroit, MI, 48202, USA. lstein1@hfhs.org.<br /><searchLink fieldCode="AU" term="%22Alonso-Llamazares+J%22">Alonso-Llamazares J</searchLink>; Driven Research LLC, Coral Gables, FL, USA.<br /><searchLink fieldCode="AU" term="%22Draelos+ZD%22">Draelos ZD</searchLink>; Dermatology Consulting Services, High Point, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gooderham+MJ%22">Gooderham MJ</searchLink>; SKiN Centre for Dermatology, Probity Medical Research and Queen's University, Peterborough, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Kempers+SE%22">Kempers SE</searchLink>; Minnesota Clinical Study Center, New Brighton, MN, USA.<br /><searchLink fieldCode="AU" term="%22Kircik+LH%22">Kircik LH</searchLink>; Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Indiana Medical Center, Indianapolis, IN, USA.; Physicians Skin Care, PLLC, Louisville, KY, USA.; Skin Sciences, PLLC, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Lebwohl+MG%22">Lebwohl MG</searchLink>; Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Papp+KA%22">Papp KA</searchLink>; Probity Medical Research and K Papp Clinical Research, Waterloo, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Pariser+DM%22">Pariser DM</searchLink>; Department of Dermatology, Eastern Virginia Medical School and Virginia Clinical Research, Inc., Norfolk, VA, USA.<br /><searchLink fieldCode="AU" term="%22Toth+DP%22">Toth DP</searchLink>; XLR8 Medical Research, Probity Medical Research, Windsor, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Yosipovitch+G%22">Yosipovitch G</searchLink>; University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Higham+RC%22">Higham RC</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, CA, USA.<br /><searchLink fieldCode="AU" term="%22Feng+A%22">Feng A</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, CA, USA.<br /><searchLink fieldCode="AU" term="%22Berk+DR%22">Berk DR</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%22100895290%22">American journal of clinical dermatology</searchLink> [Am J Clin Dermatol] 2023 Mar; Vol. 24 (2), pp. 305-313. <i>Date of Electronic Publication: </i>2022 Nov 12.
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