High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry.
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| Title: | High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry. |
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| Authors: | Wu Z; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Wang H; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. Electronic address: wang_hongx@hotmail.com., Wu J; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Huang Y; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Zhao X; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Nguyen JB; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Rosconi MP; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Pyles EA; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Qiu H; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. Electronic address: haibo.qiu@regeneron.com., Li N; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. |
| Source: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Jan 20; Vol. 223, pp. 115147. Date of Electronic Publication: 2022 Nov 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36399907 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wu+Z%22">Wu Z</searchLink>; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. Electronic address: wang&#95;hongx@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+JB%22">Nguyen JB</searchLink>; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rosconi+MP%22">Rosconi MP</searchLink>; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pyles+EA%22">Pyles EA</searchLink>; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Qiu+H%22">Qiu H</searchLink>; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. Electronic address: haibo.qiu@regeneron.com.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228309336%22">Journal of pharmaceutical and biomedical analysis</searchLink> [J Pharm Biomed Anal] 2023 Jan 20; Vol. 223, pp. 115147. <i>Date of Electronic Publication: </i>2022 Nov 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8309336 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-264X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207317085%22">07317085 </searchLink><i>NLM ISO Abbreviation: </i>J Pharm Biomed Anal <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36399907 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jpba.2022.115147 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 115147 Titles: – TitleFull: High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wu Z – PersonEntity: Name: NameFull: Wang H – PersonEntity: Name: NameFull: Wu J – PersonEntity: Name: NameFull: Huang Y – PersonEntity: Name: NameFull: Zhao X – PersonEntity: Name: NameFull: Nguyen JB – PersonEntity: Name: NameFull: Rosconi MP – PersonEntity: Name: NameFull: Pyles EA – PersonEntity: Name: NameFull: Qiu H – PersonEntity: Name: NameFull: Li N IsPartOfRelationships: – BibEntity: Dates: – D: 20 M: 01 Text: 2023 Jan 20 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1873-264X Numbering: – Type: volume Value: 223 Titles: – TitleFull: Journal of pharmaceutical and biomedical analysis Type: main |
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