High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry.
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| Title: | High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry. |
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| Authors: | Wu Z; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Wang H; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. Electronic address: wang_hongx@hotmail.com., Wu J; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Huang Y; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Zhao X; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Nguyen JB; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Rosconi MP; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Pyles EA; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Qiu H; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. Electronic address: haibo.qiu@regeneron.com., Li N; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. |
| Source: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Jan 20; Vol. 223, pp. 115147. Date of Electronic Publication: 2022 Nov 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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