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Feedback between mechanosensitive signaling and active forces governs endothelial junction integrity.

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Title: Feedback between mechanosensitive signaling and active forces governs endothelial junction integrity.
Authors: McEvoy E; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Biomedical Engineering, University of Galway, Galway, H91 HX31, Ireland., Sneh T; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA., Moeendarbary E; Department of Mechanical Engineering, University College London, London, WC1E 7JE, UK.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Javanmardi Y; Department of Mechanical Engineering, University College London, London, WC1E 7JE, UK., Efimova N; Department of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Yang C; Department of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Marino-Bravante GE; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.; Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Chen X; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Escribano J; Department of Mechanical Engineering, University of Zaragoza, Zaragoza, Spain., Spill F; School of Mathematics, University of Birmingham, Birmingham, B15 2TT, United Kingdom., Garcia-Aznar JM; Department of Mechanical Engineering, University of Zaragoza, Zaragoza, Spain., Weeraratna AT; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.; Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Svitkina TM; Department of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Kamm RD; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Shenoy VB; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA. vshenoy@seas.upenn.edu.; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA. vshenoy@seas.upenn.edu.
Source: Nature communications [Nat Commun] 2022 Nov 19; Vol. 13 (1), pp. 7089. Date of Electronic Publication: 2022 Nov 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22McEvoy+E%22">McEvoy E</searchLink>; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Biomedical Engineering, University of Galway, Galway, H91 HX31, Ireland.<br /><searchLink fieldCode="AU" term="%22Sneh+T%22">Sneh T</searchLink>; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.<br /><searchLink fieldCode="AU" term="%22Moeendarbary+E%22">Moeendarbary E</searchLink>; Department of Mechanical Engineering, University College London, London, WC1E 7JE, UK.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Javanmardi+Y%22">Javanmardi Y</searchLink>; Department of Mechanical Engineering, University College London, London, WC1E 7JE, UK.<br /><searchLink fieldCode="AU" term="%22Efimova+N%22">Efimova N</searchLink>; Department of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; Department of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Marino-Bravante+GE%22">Marino-Bravante GE</searchLink>; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.; Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Escribano+J%22">Escribano J</searchLink>; Department of Mechanical Engineering, University of Zaragoza, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Spill+F%22">Spill F</searchLink>; School of Mathematics, University of Birmingham, Birmingham, B15 2TT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Garcia-Aznar+JM%22">Garcia-Aznar JM</searchLink>; Department of Mechanical Engineering, University of Zaragoza, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Weeraratna+AT%22">Weeraratna AT</searchLink>; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.; Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Svitkina+TM%22">Svitkina TM</searchLink>; Department of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Kamm+RD%22">Kamm RD</searchLink>; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Shenoy+VB%22">Shenoy VB</searchLink>; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA. vshenoy@seas.upenn.edu.; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, 19104, USA. vshenoy@seas.upenn.edu.
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