View in EDS HTML Full Text PDF Full Text

Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes.

Saved in:
Bibliographic Details
Title: Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes.
Authors: Zhang JY; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Hamey F; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Trzupek D; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Mickunas M; Department of Immunobiology, King's College London, School of Immunology and Microbial Sciences, London, UK., Lee M; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Godfrey L; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Yang JHM; Department of Immunobiology, King's College London, School of Immunology and Microbial Sciences, London, UK., Pekalski ML; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Kennet J; Wellcome-MRC Institute of Metabolic Science, Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke's Biomedical Campus, Cambridge, UK., Waldron-Lynch F; Vertex Pharmaceuticals, Vertex Cell & Gene Therapies, Boston, MA, USA., Evans ML; Wellcome-MRC Institute of Metabolic Science, Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke's Biomedical Campus, Cambridge, UK., Tree TIM; Department of Immunobiology, King's College London, School of Immunology and Microbial Sciences, London, UK., Wicker LS; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Todd JA; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. john.todd@well.ox.ac.uk., Ferreira RC; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. ricardo.ferreira@well.ox.ac.uk.
Source: Nature communications [Nat Commun] 2022 Nov 28; Vol. 13 (1), pp. 7324. Date of Electronic Publication: 2022 Nov 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36443294
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Low-dose IL-2 reduces IL-21<superscript>+</superscript> T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Zhang+JY%22">Zhang JY</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hamey+F%22">Hamey F</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Trzupek+D%22">Trzupek D</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mickunas+M%22">Mickunas M</searchLink>; Department of Immunobiology, King's College London, School of Immunology and Microbial Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Godfrey+L%22">Godfrey L</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Yang+JHM%22">Yang JHM</searchLink>; Department of Immunobiology, King's College London, School of Immunology and Microbial Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Pekalski+ML%22">Pekalski ML</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kennet+J%22">Kennet J</searchLink>; Wellcome-MRC Institute of Metabolic Science, Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke's Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Waldron-Lynch+F%22">Waldron-Lynch F</searchLink>; Vertex Pharmaceuticals, Vertex Cell & Gene Therapies, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Evans+ML%22">Evans ML</searchLink>; Wellcome-MRC Institute of Metabolic Science, Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke's Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tree+TIM%22">Tree TIM</searchLink>; Department of Immunobiology, King's College London, School of Immunology and Microbial Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Wicker+LS%22">Wicker LS</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Todd+JA%22">Todd JA</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. john.todd@well.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ferreira+RC%22">Ferreira RC</searchLink>; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. ricardo.ferreira@well.ox.ac.uk.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Nov 28; Vol. 13 (1), pp. 7324. <i>Date of Electronic Publication: </i>2022 Nov 28.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36443294
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-022-34162-3
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 7324
    Titles:
      – TitleFull: Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Zhang JY
      – PersonEntity:
          Name:
            NameFull: Hamey F
      – PersonEntity:
          Name:
            NameFull: Trzupek D
      – PersonEntity:
          Name:
            NameFull: Mickunas M
      – PersonEntity:
          Name:
            NameFull: Lee M
      – PersonEntity:
          Name:
            NameFull: Godfrey L
      – PersonEntity:
          Name:
            NameFull: Yang JHM
      – PersonEntity:
          Name:
            NameFull: Pekalski ML
      – PersonEntity:
          Name:
            NameFull: Kennet J
      – PersonEntity:
          Name:
            NameFull: Waldron-Lynch F
      – PersonEntity:
          Name:
            NameFull: Evans ML
      – PersonEntity:
          Name:
            NameFull: Tree TIM
      – PersonEntity:
          Name:
            NameFull: Wicker LS
      – PersonEntity:
          Name:
            NameFull: Todd JA
      – PersonEntity:
          Name:
            NameFull: Ferreira RC
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 28
              M: 11
              Text: 2022 Nov 28
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 13
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1