Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study.

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Title: Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study.
Authors: Chang GH; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Head and Neck Infection Treatment Center, Chang Gung memorial Hospital, Chiayi, Taiwan., Yang PR; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Cheng YC; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Hsu KH; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Wu CY; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Yang YH; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin YS; Department of Pharmacy, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan., Hsu CM; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Tsai MS; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Tsai YT; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Chang PJ; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan. a9244@cgmh.org.tw.
Source: BMC complementary medicine and therapies [BMC Complement Med Ther] 2022 Nov 29; Vol. 22 (1), pp. 313. Date of Electronic Publication: 2022 Nov 29.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101761232 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-7671 (Electronic) Linking ISSN: 26627671 NLM ISO Abbreviation: BMC Complement Med Ther Subsets: MEDLINE
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  Data: Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study.
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  Data: <searchLink fieldCode="AU" term="%22Chang+GH%22">Chang GH</searchLink>; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Head and Neck Infection Treatment Center, Chang Gung memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+PR%22">Yang PR</searchLink>; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+YC%22">Cheng YC</searchLink>; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+KH%22">Hsu KH</searchLink>; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CY%22">Wu CY</searchLink>; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+YH%22">Yang YH</searchLink>; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YS%22">Lin YS</searchLink>; Department of Pharmacy, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CM%22">Hsu CM</searchLink>; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+MS%22">Tsai MS</searchLink>; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+YT%22">Tsai YT</searchLink>; Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+PJ%22">Chang PJ</searchLink>; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan. a9244@cgmh.org.tw.
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  Data: <searchLink fieldCode="JN" term="%22101761232%22">BMC complementary medicine and therapies</searchLink> [BMC Complement Med Ther] 2022 Nov 29; Vol. 22 (1), pp. 313. <i>Date of Electronic Publication: </i>2022 Nov 29.
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