A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.

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Title: A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.
Authors: Hackstein CP; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Costigan D; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Drexhage L; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Pearson C; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK., Bullers S; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK., Ilott N; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK., Akther HD; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gu Y; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK., FitzPatrick MEB; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Harrison OJ; Center for Fundamental Immunology, Benaroya Research Institute, 1201 9th Ave, Seattle, WA, 98101, USA.; Department of Immunology, University of Washington, 750 Republican St, Seattle, WA, 98108, USA., Garner LC; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Mann EH; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK., Pandey S; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Friedrich M; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK., Provine NM; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Uhlig HH; Translational Gastroenterology Unit, and Biomedical Research Centre, and Department of Paediatrics, University of Oxford, Oxford, OX39DU, UK., Marchi E; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Powrie F; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK., Klenerman P; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK. paul.klenerman@ndm.ox.ac.uk.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. paul.klenerman@ndm.ox.ac.uk., Thornton EE; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. emily.thornton@imm.ox.ac.uk.; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK. emily.thornton@imm.ox.ac.uk.; Nuffield Department of Medicine, University of Oxford, Oxford, UK. emily.thornton@imm.ox.ac.uk.
Source: Nature communications [Nat Commun] 2022 Dec 03; Vol. 13 (1), pp. 7472. Date of Electronic Publication: 2022 Dec 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-35126-3