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Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology.

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Title: Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology.
Authors: Kvedaraite E; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Pathology, Karolinska University Laboratory, Stockholm, Sweden., Milne P; Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK.; Northern Centre for Cancer Care, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK., Khalilnezhad A; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chevrier M; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Sethi R; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Lee HK; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Hagey DW; Clinical Research Center, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., von Bahr Greenwood T; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Pediatric Oncology, Astrid Lindgrens Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Mouratidou N; Pediatric Gastroenterology, Hepatology and Nutrition Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Jädersten M; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.; Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden., Lee NYS; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Minnerup L; Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany., Tan Y; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.; National Skin Center, National Healthcare Group, Singapore, Singapore., Dutertre CA; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France., Benac N; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.; Université de Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, Bordeaux, France., Hwang YY; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Lum J; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Loh AHP; VIVA-KKH Paediatric Brain and Solid Tumour Programme, KK Women's and Children's Hospital, Singapore, Singapore., Jansson J; Pediatric Gastroenterology, Hepatology and Nutrition Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Teng KWW; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Khalilnezhad S; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Xu W; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Resteu A; Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK.; Northern Centre for Cancer Care, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK., Tey HL; National Skin Center, National Healthcare Group, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Guan NL; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Larbi A; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Howland SW; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore., Arnell H; Pediatric Gastroenterology, Hepatology and Nutrition Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Andaloussi SEL; Clinical Research Center, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., Braier J; Pathology Department, Hospital Nacional de Pediatría Dr Prof JP Garrahan, Buenos Aires, Argentina., Rassidakis G; Department of Clinical Pathology, Karolinska University Laboratory, Stockholm, Sweden., Galluzzo L; Pathology Department, Hospital Nacional de Pediatría Dr Prof JP Garrahan, Buenos Aires, Argentina., Dzionek A; Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany., Henter JI; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Pediatric Oncology, Astrid Lindgrens Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Chen J; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.; Immunology Translational Research Program, Yong Loo Lin School of Medicine, Department of Microbiology and Immunology, National University of Singapore (NUS), Singapore, Singapore., Collin M; Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK.; Northern Centre for Cancer Care, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK., Ginhoux F; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.; Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; SingHealth Duke-NUS Academic Medical Centre, Translational Immunology Institute, Singapore, Singapore.
Source: Science immunology [Sci Immunol] 2022 Dec 23; Vol. 7 (78), pp. eadd3330. Date of Electronic Publication: 2022 Dec 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
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  Data: Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology.
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  Data: <searchLink fieldCode="AU" term="%22Kvedaraite+E%22">Kvedaraite E</searchLink>; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Pathology, Karolinska University Laboratory, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Milne+P%22">Milne P</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK.; Northern Centre for Cancer Care, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Khalilnezhad+A%22">Khalilnezhad A</searchLink>; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chevrier+M%22">Chevrier M</searchLink>; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Sethi+R%22">Sethi R</searchLink>; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+HK%22">Lee HK</searchLink>; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Hagey+DW%22">Hagey DW</searchLink>; Clinical Research Center, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22von+Bahr+Greenwood+T%22">von Bahr Greenwood T</searchLink>; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Pediatric Oncology, Astrid Lindgrens Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Mouratidou+N%22">Mouratidou N</searchLink>; Pediatric Gastroenterology, Hepatology and Nutrition Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Jädersten+M%22">Jädersten M</searchLink>; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.; Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Lee+NYS%22">Lee NYS</searchLink>; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Minnerup+L%22">Minnerup L</searchLink>; Miltenyi Biotec B.V. & Co. 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