View in EDS HTML Full Text PDF Full Text

Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.

Saved in:
Bibliographic Details
Title: Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
Authors: Zhu L; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Kamalathevan P; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Koneva LA; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Zarebska JM; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Chanalaris A; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Ismail H; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.; Healthy Lifespan Institute (HELSI) and Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK., Wiberg A; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Ng M; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Muhammad H; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Walsby-Tickle J; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., McCullagh JSO; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., Watt FE; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.; Centre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, UK., Sansom SN; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Furniss D; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Gardiner MD; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Vincent TL; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Riley N, Spiteri M, McNab I, Little C, Cogswell L, Critchley P, Giele H, Shirley R
Corporate Authors: Oxford Hand Surgical Team; Department of Orthopaedics and Plastic Surgery, Nuffield Orthopedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LD, UK.
Source: Science translational medicine [Sci Transl Med] 2022 Dec 21; Vol. 14 (676), pp. eabm4054. Date of Electronic Publication: 2022 Dec 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36542696
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Kamalathevan+P%22">Kamalathevan P</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Koneva+LA%22">Koneva LA</searchLink>; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Zarebska+JM%22">Zarebska JM</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Chanalaris+A%22">Chanalaris A</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Ismail+H%22">Ismail H</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.; Healthy Lifespan Institute (HELSI) and Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK.<br /><searchLink fieldCode="AU" term="%22Wiberg+A%22">Wiberg A</searchLink>; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK.<br /><searchLink fieldCode="AU" term="%22Ng+M%22">Ng M</searchLink>; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK.<br /><searchLink fieldCode="AU" term="%22Muhammad+H%22">Muhammad H</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Walsby-Tickle+J%22">Walsby-Tickle J</searchLink>; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.<br /><searchLink fieldCode="AU" term="%22McCullagh+JSO%22">McCullagh JSO</searchLink>; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.<br /><searchLink fieldCode="AU" term="%22Watt+FE%22">Watt FE</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.; Centre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Sansom+SN%22">Sansom SN</searchLink>; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Furniss+D%22">Furniss D</searchLink>; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK.<br /><searchLink fieldCode="AU" term="%22Gardiner+MD%22">Gardiner MD</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Vincent+TL%22">Vincent TL</searchLink>; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.<br /><searchLink fieldCode="AU" term="%22Riley+N%22">Riley N</searchLink><br /><searchLink fieldCode="AU" term="%22Spiteri+M%22">Spiteri M</searchLink><br /><searchLink fieldCode="AU" term="%22McNab+I%22">McNab I</searchLink><br /><searchLink fieldCode="AU" term="%22Little+C%22">Little C</searchLink><br /><searchLink fieldCode="AU" term="%22Cogswell+L%22">Cogswell L</searchLink><br /><searchLink fieldCode="AU" term="%22Critchley+P%22">Critchley P</searchLink><br /><searchLink fieldCode="AU" term="%22Giele+H%22">Giele H</searchLink><br /><searchLink fieldCode="AU" term="%22Shirley+R%22">Shirley R</searchLink>
– Name: AuthorCorporate
  Label: Corporate Authors
  Group: Au
  Data: <searchLink fieldCode="CA" term="%22Oxford+Hand+Surgical+Team%22">Oxford Hand Surgical Team</searchLink>; Department of Orthopaedics and Plastic Surgery, Nuffield Orthopedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LD, UK.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2022 Dec 21; Vol. 14 (676), pp. eabm4054. <i>Date of Electronic Publication: </i>2022 Dec 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36542696
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/scitranslmed.abm4054
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: eabm4054
    Titles:
      – TitleFull: Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Zhu L
      – PersonEntity:
          Name:
            NameFull: Kamalathevan P
      – PersonEntity:
          Name:
            NameFull: Koneva LA
      – PersonEntity:
          Name:
            NameFull: Zarebska JM
      – PersonEntity:
          Name:
            NameFull: Chanalaris A
      – PersonEntity:
          Name:
            NameFull: Ismail H
      – PersonEntity:
          Name:
            NameFull: Wiberg A
      – PersonEntity:
          Name:
            NameFull: Ng M
      – PersonEntity:
          Name:
            NameFull: Muhammad H
      – PersonEntity:
          Name:
            NameFull: Walsby-Tickle J
      – PersonEntity:
          Name:
            NameFull: McCullagh JSO
      – PersonEntity:
          Name:
            NameFull: Watt FE
      – PersonEntity:
          Name:
            NameFull: Sansom SN
      – PersonEntity:
          Name:
            NameFull: Furniss D
      – PersonEntity:
          Name:
            NameFull: Gardiner MD
      – PersonEntity:
          Name:
            NameFull: Vincent TL
      – PersonEntity:
          Name:
            NameFull: Riley N
      – PersonEntity:
          Name:
            NameFull: Spiteri M
      – PersonEntity:
          Name:
            NameFull: McNab I
      – PersonEntity:
          Name:
            NameFull: Little C
      – PersonEntity:
          Name:
            NameFull: Cogswell L
      – PersonEntity:
          Name:
            NameFull: Critchley P
      – PersonEntity:
          Name:
            NameFull: Giele H
      – PersonEntity:
          Name:
            NameFull: Shirley R
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 21
              M: 12
              Text: 2022 Dec 21
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1946-6242
          Numbering:
            – Type: volume
              Value: 14
            – Type: issue
              Value: 676
          Titles:
            – TitleFull: Science translational medicine
              Type: main
ResultId 1