Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial.

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Title: Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial.
Authors: Stoll F; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Seidel-Glätzer A; Coordination Centre for Clinical Trials (KKS) Heidelberg, 69120 Heidelberg, Germany., Burghaus I; Coordination Centre for Clinical Trials (KKS) Heidelberg, 69120 Heidelberg, Germany., Göring O; Coordination Centre for Clinical Trials (KKS) Heidelberg, 69120 Heidelberg, Germany., Sauter M; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Rose P; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Daniel V; Institute of Immunology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Haag M; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tuebingen, 72076 Tuebingen, Germany., Schwab M; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tuebingen, 72076 Tuebingen, Germany.; Departments of Clinical Pharmacology, and of Biochemistry and Pharmacy, University of Tuebingen, 72076 Tuebingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, 72076 Tübingen, Germany., Riffel J; Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, 69120 Heidelberg, Germany., André F; Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Taylor L; Pharmacy, Heidelberg University Hospital, 69120 Heidelberg, Germany., Weiss J; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Burhenne J; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Cleeves V; Technology Transfer Heidelberg GmbH, 69120 Heidelberg, Germany., Haefeli WE; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Blank A; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Source: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 14; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 14.
Publication Type: Clinical Trial, Phase I; Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Stoll+F%22">Stoll F</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Seidel-Glätzer+A%22">Seidel-Glätzer A</searchLink>; Coordination Centre for Clinical Trials (KKS) Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Burghaus+I%22">Burghaus I</searchLink>; Coordination Centre for Clinical Trials (KKS) Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Göring+O%22">Göring O</searchLink>; Coordination Centre for Clinical Trials (KKS) Heidelberg, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sauter+M%22">Sauter M</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Rose+P%22">Rose P</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Daniel+V%22">Daniel V</searchLink>; Institute of Immunology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Haag+M%22">Haag M</searchLink>; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tuebingen, 72076 Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schwab+M%22">Schwab M</searchLink>; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tuebingen, 72076 Tuebingen, Germany.; Departments of Clinical Pharmacology, and of Biochemistry and Pharmacy, University of Tuebingen, 72076 Tuebingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Riffel+J%22">Riffel J</searchLink>; Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22André+F%22">André F</searchLink>; Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Taylor+L%22">Taylor L</searchLink>; Pharmacy, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Weiss+J%22">Weiss J</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Burhenne+J%22">Burhenne J</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Cleeves+V%22">Cleeves V</searchLink>; Technology Transfer Heidelberg GmbH, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Haefeli+WE%22">Haefeli WE</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Blank+A%22">Blank A</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2022 Dec 14; Vol. 23 (24). <i>Date of Electronic Publication: </i>2022 Dec 14.
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