Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia.

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Title: Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia.
Authors: Wang E; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA. Electronic address: eric.wang@jax.org., Pineda JMB; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA; Medical Scientist Training Program, University of Washington, Seattle, WA, USA., Kim WJ; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chen S; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Bourcier J; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Stahl M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Hogg SJ; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Bewersdorf JP; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Han C; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA., Singer ME; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cui D; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Erickson CE; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Tittley SM; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Penson AV; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Knorr K; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Stanley RF; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rahman J; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Krishnamoorthy G; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Division of Endocrinology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fagin JA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Division of Endocrinology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Creger E; Biosplice Therapeutics Inc., San Diego, CA, USA., McMillan E; Biosplice Therapeutics Inc., San Diego, CA, USA., Mak CC; Biosplice Therapeutics Inc., San Diego, CA, USA., Jarvis M; Biosplice Therapeutics Inc., San Diego, CA, USA., Bossard C; Biosplice Therapeutics Inc., San Diego, CA, USA., Beaupre DM; Biosplice Therapeutics Inc., San Diego, CA, USA., Bradley RK; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA. Electronic address: rbradley@fredhutch.org., Abdel-Wahab O; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: abdelwao@mskcc.org.
Source: Cancer cell [Cancer Cell] 2023 Jan 09; Vol. 41 (1), pp. 164-180.e8. Date of Electronic Publication: 2022 Dec 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE
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  Data: Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Wang+E%22">Wang E</searchLink>; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA. Electronic address: eric.wang@jax.org.<br /><searchLink fieldCode="AU" term="%22Pineda+JMB%22">Pineda JMB</searchLink>; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA; Medical Scientist Training Program, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+WJ%22">Kim WJ</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bourcier+J%22">Bourcier J</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stahl+M%22">Stahl M</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hogg+SJ%22">Hogg SJ</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bewersdorf+JP%22">Bewersdorf JP</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Han+C%22">Han C</searchLink>; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.<br /><searchLink fieldCode="AU" term="%22Singer+ME%22">Singer ME</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cui+D%22">Cui D</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Erickson+CE%22">Erickson CE</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tittley+SM%22">Tittley SM</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Penson+AV%22">Penson AV</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Knorr+K%22">Knorr K</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stanley+RF%22">Stanley RF</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rahman+J%22">Rahman J</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Krishnamoorthy+G%22">Krishnamoorthy G</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Division of Endocrinology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fagin+JA%22">Fagin JA</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Division of Endocrinology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Creger+E%22">Creger E</searchLink>; Biosplice Therapeutics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22McMillan+E%22">McMillan E</searchLink>; Biosplice Therapeutics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mak+CC%22">Mak CC</searchLink>; Biosplice Therapeutics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jarvis+M%22">Jarvis M</searchLink>; Biosplice Therapeutics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bossard+C%22">Bossard C</searchLink>; Biosplice Therapeutics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Beaupre+DM%22">Beaupre DM</searchLink>; Biosplice Therapeutics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bradley+RK%22">Bradley RK</searchLink>; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA. Electronic address: rbradley@fredhutch.org.<br /><searchLink fieldCode="AU" term="%22Abdel-Wahab+O%22">Abdel-Wahab O</searchLink>; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: abdelwao@mskcc.org.
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  Data: <searchLink fieldCode="JN" term="%22101130617%22">Cancer cell</searchLink> [Cancer Cell] 2023 Jan 09; Vol. 41 (1), pp. 164-180.e8. <i>Date of Electronic Publication: </i>2022 Dec 22.
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