Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons.
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| Title: | Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons. |
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| Authors: | Parnell E; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Culotta L; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Forrest MP; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Jalloul HA; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Eckman BL; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Loizzo DD; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Horan KKE; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Dos Santos M; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Piguel NH; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois., Tai DJC; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Zhang H; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois., Gertler TS; Division of Neurology, Department of Pediatrics, Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago, Illinois; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Simkin D; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Sanders AR; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois., Talkowski ME; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Gejman PV; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois., Kiskinis E; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Duan J; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois., Penzes P; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: p-penzes@northwestern.edu. |
| Source: | Biological psychiatry [Biol Psychiatry] 2023 Jul 15; Vol. 94 (2), pp. 153-163. Date of Electronic Publication: 2022 Nov 09. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 0213264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2402 (Electronic) Linking ISSN: 00063223 NLM ISO Abbreviation: Biol Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36581494 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Parnell+E%22">Parnell E</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Culotta+L%22">Culotta L</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Forrest+MP%22">Forrest MP</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Jalloul+HA%22">Jalloul HA</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Eckman+BL%22">Eckman BL</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Loizzo+DD%22">Loizzo DD</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Horan+KKE%22">Horan KKE</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+M%22">Dos Santos M</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Piguel+NH%22">Piguel NH</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Tai+DJC%22">Tai DJC</searchLink>; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Gertler+TS%22">Gertler TS</searchLink>; Division of Neurology, Department of Pediatrics, Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago, Illinois; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Simkin+D%22">Simkin D</searchLink>; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Sanders+AR%22">Sanders AR</searchLink>; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Talkowski+ME%22">Talkowski ME</searchLink>; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Gejman+PV%22">Gejman PV</searchLink>; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Kiskinis+E%22">Kiskinis E</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Duan+J%22">Duan J</searchLink>; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Penzes+P%22">Penzes P</searchLink>; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern University Center for Autism and Neurodevelopment, Chicago, Illinois; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: p-penzes@northwestern.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220213264%22">Biological psychiatry</searchLink> [Biol Psychiatry] 2023 Jul 15; Vol. 94 (2), pp. 153-163. <i>Date of Electronic Publication: </i>2022 Nov 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0213264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2402 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200063223%22">00063223 </searchLink><i>NLM ISO Abbreviation: </i>Biol Psychiatry <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36581494 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.biopsych.2022.11.005 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 153 Titles: – TitleFull: Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Parnell E – PersonEntity: Name: NameFull: Culotta L – PersonEntity: Name: NameFull: Forrest MP – PersonEntity: Name: NameFull: Jalloul HA – PersonEntity: Name: NameFull: Eckman BL – PersonEntity: Name: NameFull: Loizzo DD – PersonEntity: Name: NameFull: Horan KKE – PersonEntity: Name: NameFull: Dos Santos M – PersonEntity: Name: NameFull: Piguel NH – PersonEntity: Name: NameFull: Tai DJC – PersonEntity: Name: NameFull: Zhang H – PersonEntity: Name: NameFull: Gertler TS – PersonEntity: Name: NameFull: Simkin D – PersonEntity: Name: NameFull: Sanders AR – PersonEntity: Name: NameFull: Talkowski ME – PersonEntity: Name: NameFull: Gejman PV – PersonEntity: Name: NameFull: Kiskinis E – PersonEntity: Name: NameFull: Duan J – PersonEntity: Name: NameFull: Penzes P IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 07 Text: 2023 Jul 15 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1873-2402 Numbering: – Type: volume Value: 94 – Type: issue Value: 2 Titles: – TitleFull: Biological psychiatry Type: main |
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