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Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.

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Title: Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
Authors: Hing ZA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Walker JS; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Whipp EC; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Brinton L; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Cannon M; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Zhang P; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Sher S; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Cempre CB; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Brown F; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Smith PL; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Agostinelli C; Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Pileri SA; European Institute of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Department of Specialized, Experimental and Diagnostic Medicine, University of Bologna, Bologna, Italy., Skinner JN; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Williams K; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Phillips H; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Shaffer J; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Beaver LP; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Pan A; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Shin K; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Gregory CT; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Ozer GH; Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA., Yilmaz SA; Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA., Harrington BK; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA.; Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA., Lehman AM; Center for Biostatistics, The Ohio State University, Columbus, OH, USA., Yu L; Center for Biostatistics, The Ohio State University, Columbus, OH, USA., Coppola V; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA., Yan P; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Scherle P; Prelude Therapeutics, Wilmington, DE, USA., Wang M; Prelude Therapeutics, Wilmington, DE, USA., Pitis P; Prelude Therapeutics, Wilmington, DE, USA., Xu C; Prelude Therapeutics, Wilmington, DE, USA., Vaddi K; Prelude Therapeutics, Wilmington, DE, USA., Chen-Kiang S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Woyach J; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Blachly JS; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Alinari L; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Yang Y; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Byrd JC; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.; Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA., Baiocchi RA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Blaser BW; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Lapalombella R; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA. rosa.lapalombella@osumc.edu.
Source: Nature communications [Nat Commun] 2023 Jan 06; Vol. 14 (1), pp. 97. Date of Electronic Publication: 2023 Jan 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
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