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Exploring the incremental utility of circulating biomarkers for robust risk prediction of incident atrial fibrillation in European cohorts using regressions and modern machine learning methods.

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Title: Exploring the incremental utility of circulating biomarkers for robust risk prediction of incident atrial fibrillation in European cohorts using regressions and modern machine learning methods.
Authors: Toprak B; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany., Brandt S; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany., Brederecke J; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany., Gianfagna F; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Via Rossi 9, 21100 Varese, Italy.; Mediterranea Cardiocentro, Via Orazio 2, 80122 Napoli, Italy., Vishram-Nielsen JKK; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.; Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark., Ojeda FM; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany., Costanzo S; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy., Börschel CS; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany., Söderberg S; Department of Public Health and Clinical Medicine, and Heart Centre, Umeå University, SE-901 87 Umeå, Sweden., Katsoularis I; Department of Public Health and Clinical Medicine, and Heart Centre, Umeå University, SE-901 87 Umeå, Sweden., Camen S; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany., Vartiainen E; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland., Donati MB; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy., Kontto J; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland., Bobak M; Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK., Mathiesen EB; Brain and Circulation Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Hansine Hansens veg 18, 9019 Tromsø, Norway., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark., Koenig W; German Heart Centre Munich, Technical University of Munich, Lazarettstraße 36, 80636 Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Biedersteinerstraße 29, 80802 Munich, Germany.; Institute of Epidemiology and Medical Biometry, University of Ulm, Helmholtzstraße 22, 89081 Ulm, Germany., Løchen ML; Department of Community Medicine, UiT The Arctic University of Norway, Hansine Hansens veg 18, 9019 Tromsø, Norway., Di Castelnuovo A; Mediterranea Cardiocentro, Via Orazio 2, 80122 Napoli, Italy., Blankenberg S; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany., de Gaetano G; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy., Kuulasmaa K; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland., Iacoviello L; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Via Rossi 9, 21100 Varese, Italy.; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy., Niiranen T; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland.; Department of Medicine, Turku University Hospital and University of Turku, Kiinamyllynkatu 4-8, 20521 Turku, Finland., Zeller T; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, Martinistraße 52, 20246 Hamburg, Germany., Schnabel RB; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany.
Source: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2023 Mar 30; Vol. 25 (3), pp. 812-819.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883649 Publication Model: Print Cited Medium: Internet ISSN: 1532-2092 (Electronic) Linking ISSN: 10995129 NLM ISO Abbreviation: Europace Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exploring the incremental utility of circulating biomarkers for robust risk prediction of incident atrial fibrillation in European cohorts using regressions and modern machine learning methods.
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  Data: <searchLink fieldCode="AU" term="%22Toprak+B%22">Toprak B</searchLink>; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Brandt+S%22">Brandt S</searchLink>; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Brederecke+J%22">Brederecke J</searchLink>; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gianfagna+F%22">Gianfagna F</searchLink>; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Via Rossi 9, 21100 Varese, Italy.; Mediterranea Cardiocentro, Via Orazio 2, 80122 Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Vishram-Nielsen+JKK%22">Vishram-Nielsen JKK</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.; Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ojeda+FM%22">Ojeda FM</searchLink>; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Costanzo+S%22">Costanzo S</searchLink>; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy.<br /><searchLink fieldCode="AU" term="%22Börschel+CS%22">Börschel CS</searchLink>; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Söderberg+S%22">Söderberg S</searchLink>; Department of Public Health and Clinical Medicine, and Heart Centre, Umeå University, SE-901 87 Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Katsoularis+I%22">Katsoularis I</searchLink>; Department of Public Health and Clinical Medicine, and Heart Centre, Umeå University, SE-901 87 Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Camen+S%22">Camen S</searchLink>; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Vartiainen+E%22">Vartiainen E</searchLink>; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Donati+MB%22">Donati MB</searchLink>; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy.<br /><searchLink fieldCode="AU" term="%22Kontto+J%22">Kontto J</searchLink>; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Bobak+M%22">Bobak M</searchLink>; Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK.<br /><searchLink fieldCode="AU" term="%22Mathiesen+EB%22">Mathiesen EB</searchLink>; Brain and Circulation Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Hansine Hansens veg 18, 9019 Tromsø, Norway.<br /><searchLink fieldCode="AU" term="%22Linneberg+A%22">Linneberg A</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Koenig+W%22">Koenig W</searchLink>; German Heart Centre Munich, Technical University of Munich, Lazarettstraße 36, 80636 Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Biedersteinerstraße 29, 80802 Munich, Germany.; Institute of Epidemiology and Medical Biometry, University of Ulm, Helmholtzstraße 22, 89081 Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Løchen+ML%22">Løchen ML</searchLink>; Department of Community Medicine, UiT The Arctic University of Norway, Hansine Hansens veg 18, 9019 Tromsø, Norway.<br /><searchLink fieldCode="AU" term="%22Di+Castelnuovo+A%22">Di Castelnuovo A</searchLink>; Mediterranea Cardiocentro, Via Orazio 2, 80122 Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Blankenberg+S%22">Blankenberg S</searchLink>; Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site, Hamburg/Kiel/Luebeck, Potsdamer Straße 58, 10785 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22de+Gaetano+G%22">de Gaetano G</searchLink>; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy.<br /><searchLink fieldCode="AU" term="%22Kuulasmaa+K%22">Kuulasmaa K</searchLink>; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Salomaa+V%22">Salomaa V</searchLink>; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Iacoviello+L%22">Iacoviello L</searchLink>; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Via Rossi 9, 21100 Varese, Italy.; Department of Epidemiology and Prevention, IRCCS Neuromed, Via dell´ Elettronica, 86077 Pozzilli, Italy.<br /><searchLink fieldCode="AU" term="%22Niiranen+T%22">Niiranen T</searchLink>; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, POB 30, Mannerheimintie 166, 00271 Helsinki, Finland.; 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