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Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression.

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Title: Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression.
Authors: Guillot A; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Winkler M; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Silva Afonso M; Department of Fibrosis Biology, Gilead Sciences, Foster City, California, USA., Aggarwal A; Department of Nonclinical safety & Pathobiology, Gilead Sciences, Foster City, California, USA., Lopez D; Department of Research Data Sciences, Gilead Sciences, Foster City, California, USA., Berger H; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Kohlhepp MS; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Liu H; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Özdirik B; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Eschrich J; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Ma J; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH, Bethesda, Maryland, USA., Peiseler M; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Heymann F; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Pendem S; Department of Fibrosis Biology, Gilead Sciences, Foster City, California, USA., Mahadevan S; Department of Nonclinical safety & Pathobiology, Gilead Sciences, Foster City, California, USA., Gao B; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH, Bethesda, Maryland, USA., Diehl L; Department of Nonclinical safety & Pathobiology, Gilead Sciences, Foster City, California, USA., Gupta R; Department of Fibrosis Biology, Gilead Sciences, Foster City, California, USA., Tacke F; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.
Source: Hepatology (Baltimore, Md.) [Hepatology] 2023 Jul 01; Vol. 78 (1), pp. 150-166. Date of Electronic Publication: 2023 Jan 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural
Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression.
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  Data: <searchLink fieldCode="AU" term="%22Guillot+A%22">Guillot A</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Winkler+M%22">Winkler M</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Silva+Afonso+M%22">Silva Afonso M</searchLink>; Department of Fibrosis Biology, Gilead Sciences, Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Aggarwal+A%22">Aggarwal A</searchLink>; Department of Nonclinical safety & Pathobiology, Gilead Sciences, Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Lopez+D%22">Lopez D</searchLink>; Department of Research Data Sciences, Gilead Sciences, Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Berger+H%22">Berger H</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kohlhepp+MS%22">Kohlhepp MS</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Özdirik+B%22">Özdirik B</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Eschrich+J%22">Eschrich J</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ma+J%22">Ma J</searchLink>; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Peiseler+M%22">Peiseler M</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Heymann+F%22">Heymann F</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Pendem+S%22">Pendem S</searchLink>; Department of Fibrosis Biology, Gilead Sciences, Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Mahadevan+S%22">Mahadevan S</searchLink>; Department of Nonclinical safety & Pathobiology, Gilead Sciences, Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Gao+B%22">Gao B</searchLink>; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Diehl+L%22">Diehl L</searchLink>; Department of Nonclinical safety & Pathobiology, Gilead Sciences, Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+R%22">Gupta R</searchLink>; Department of Fibrosis Biology, Gilead Sciences, Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Tacke+F%22">Tacke F</searchLink>; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.
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  Data: <searchLink fieldCode="JN" term="%228302946%22">Hepatology (Baltimore, Md.)</searchLink> [Hepatology] 2023 Jul 01; Vol. 78 (1), pp. 150-166. <i>Date of Electronic Publication: </i>2023 Jan 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+Inc%22">Wolters Kluwer Health, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8302946 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-3350 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202709139%22">02709139 </searchLink><i>NLM ISO Abbreviation: </i>Hepatology <i>Subsets: </i>MEDLINE
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