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Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.

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Title: Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.
Authors: Linke F; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Johnson JEC; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Kern S; School of Pharmacy, University of Nottingham, Nottingham, UK., Bennett CD; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Birmingham Children's Hospital, Birmingham, UK., Lourdusamy A; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Lea D; Digital Research Service, University of Nottingham, Nottingham, UK., Clifford SC; Wolfson Childhood Cancer Research Centre, Translational & Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle Upon Tyne, NE1 7RU, UK., Merry CLR; School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Stolnik S; School of Pharmacy, University of Nottingham, Nottingham, UK., Alexander MR; School of Pharmacy, University of Nottingham, Nottingham, UK., Peet AC; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Birmingham Children's Hospital, Birmingham, UK., Scurr DJ; School of Pharmacy, University of Nottingham, Nottingham, UK., Griffiths RL; School of Pharmacy, University of Nottingham, Nottingham, UK., Grabowska AM; School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Kerr ID; School of Life Sciences, University of Nottingham, Nottingham, UK., Coyle B; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK. beth.coyle@nottingham.ac.uk.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Jan 11; Vol. 11 (1), pp. 6. Date of Electronic Publication: 2023 Jan 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.
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